Nutrition & Metabolism

Table 2 Statistical analysis results of the main metabolite change in feces

From: Metabolomics insights into the modulatory effects of long-term compound polysaccharide intake in high-fat diet-induced obese rats

Metabolites	Group HFD vs CD			Group LF vs HFD
Metabolites	p value†	Adjust p value‡	Trend	p value†	Adjust p value‡	Trend
Imidazole	0.0002	0.0006	↑**
Urocanate	< 0.0001	< 0.0001	↑**	0.0197	0.0395	↑*
3-Phenylpropionate	< 0.0001	< 0.0001	↑**	0.0245	0.0429	↑*
Glutamate	< 0.0001	0.0001	↑**
Phenylacetate	< 0.0001	< 0.0001	↑**	0.0268	0.0418	↑*
Tyrosine	< 0.0001	< 0.0001	↑**	0.0017	0.0120	↑**
Cadaverine	0.0005	0.0011	↑**	0.0175	0.0409	↑*
Valine	0.0002	0.0005	↑**
Leucine	0.0013	0.0025	↑**
5-Aminovalerate	0.0229	0.0253	↑*
Uracil	0.0332	0.0349	↑*	0.0064	0.0224	↑**
Arginine	0.0003	0.0008	↑**
Creatine	0.0002	0.0005	↑**	0.0347	0.0442	↑*
Malonate	0.0066	0.0093	↑**
α-Ketoisocaproate	0.0080	0.0106	↑**
Methylamine	0.0005	0.0011	↑**
2-Oxoglutarate	0.0022	0.0039	↓**	0.0479	0.0479	↑*
Threonine	0.0066	0.0098	↓**
Lactate	0.0125	0.0154	↓*
α-D-Xylp	0.0041	0.0066	↓**
α-Arabinose	0.0341	0.0341	↓*
Succinate	0.0148	0.0173	↓*
Choline	0.0046	0.0074	↓**
Pyruvate				< 0.0001	< 0.0001	↑**
Imidazole				0.0034	0.0160	↑**
Malate				0.0079	0.0222	↑*
Cytidine				0.0452	0.0487	↑*
Uridine				0.0357	0.0416	↑*
Taurine				0.0283	0.0396	↓*

Abbreviations: α-D-Xylp α-D-xylopyranosyl
†From Student t test. *p < 0.05; **p < 0.01. ‡Adjusted by false discovery rate method across the metabolites within each comparison. HFD vs CD: compare HFD to CD; LF vs HFD: compare LF to HFD

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ISSN: 1743-7075

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