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Table 2 Statistical analysis results of the main metabolite change in feces

From: Metabolomics insights into the modulatory effects of long-term compound polysaccharide intake in high-fat diet-induced obese rats

Metabolites Group HFD vs CD Group LF vs HFD
p value† Adjust p value‡ Trend p value† Adjust p value‡ Trend
Imidazole 0.0002 0.0006 ↑**    
Urocanate < 0.0001 < 0.0001 ↑** 0.0197 0.0395 ↑*
3-Phenylpropionate < 0.0001 < 0.0001 ↑** 0.0245 0.0429 ↑*
Glutamate < 0.0001 0.0001 ↑**    
Phenylacetate < 0.0001 < 0.0001 ↑** 0.0268 0.0418 ↑*
Tyrosine < 0.0001 < 0.0001 ↑** 0.0017 0.0120 ↑**
Cadaverine 0.0005 0.0011 ↑** 0.0175 0.0409 ↑*
Valine 0.0002 0.0005 ↑**    
Leucine 0.0013 0.0025 ↑**    
5-Aminovalerate 0.0229 0.0253 ↑*    
Uracil 0.0332 0.0349 ↑* 0.0064 0.0224 ↑**
Arginine 0.0003 0.0008 ↑**    
Creatine 0.0002 0.0005 ↑** 0.0347 0.0442 ↑*
Malonate 0.0066 0.0093 ↑**    
α-Ketoisocaproate 0.0080 0.0106 ↑**    
Methylamine 0.0005 0.0011 ↑**    
2-Oxoglutarate 0.0022 0.0039 ↓** 0.0479 0.0479 ↑*
Threonine 0.0066 0.0098 ↓**    
Lactate 0.0125 0.0154 ↓*    
α-D-Xylp 0.0041 0.0066 ↓**    
α-Arabinose 0.0341 0.0341 ↓*    
Succinate 0.0148 0.0173 ↓*    
Choline 0.0046 0.0074 ↓**    
Pyruvate     < 0.0001 < 0.0001 ↑**
Imidazole     0.0034 0.0160 ↑**
Malate     0.0079 0.0222 ↑*
Cytidine     0.0452 0.0487 ↑*
Uridine     0.0357 0.0416 ↑*
Taurine     0.0283 0.0396 ↓*
  1. Abbreviations: α-D-Xylp α-D-xylopyranosyl
  2. †From Student t test. *p < 0.05; **p < 0.01. ‡Adjusted by false discovery rate method across the metabolites within each comparison. HFD vs CD: compare HFD to CD; LF vs HFD: compare LF to HFD