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Table 4 Oxidative stress

From: Dietary canolol protects the heart against the deleterious effects induced by the association of rapeseed oil, vitamin E and coenzyme Q10 in the context of a high-fat diet

  C PS R RTC RTCC
Thiols 55 ± 1a 57 ± 1a 64 ± 1b 62 ± 2b 65 ± 1b
TBARS 0.29 ± 0.01a 0.23 ± 0.01b 0.23 ± 0.02b 0.24 ± 0.02b 0.24 ± 0.01b
FRAP 107 ± 4a 96 ± 3c 88 ± 2cb 88 ± 3cb 86 ± 3b
SOD activity 358 ± 55a 170 ± 20b 167 ± 15b 158 ± 11b 132 ± 21b
GPX activity 1062 ± 22a 1065 ± 28a 1066 ± 26a 1160 ± 25b 1096 ± 26ab
SOD2 0.41 ± 0.03a 0.55 ± 0.09a 0.57 ± 0.08a 0.83 ± 0.10b 0.57 ± 0.08a
GPX4 0.54 ± 0.01a 0.59 ± 0.02ab 0.55 ± 0.03a 0.66 ± 0.04b 0.64 ± 0.04b
Cat 0.30 ± 0.05a 0.51 ± 0.11ab 0.57 ± 0.09ab 0.79 ± 0.15b 0.56 ± 0.11ab
  1. C control rats, PS rats fed a palm oil/sunflower oil mixture, R rats fed rapeseed oil, RTC rats fed rapeseed oil enriched with α-tocopherol and coenzyme Q10, RTCC rats fed RTC plus canolol, TBARS thiobarbituric acid reactive substances, FRAP ferric reducing antioxidant power, SOD superoxide dismutase, GPX glutathione peroxidase, SOD2, GPX4 and Cat SOD2, GPX4 and catalase mRNA expression. Thiols, TBARS and FRAP are expressed in μmoles/g of proteins. SOD and GPX activities are expressed in in U/g of proteins. Averages of 12 rats per group
  2. a, b, cmeans in a row without a common letter are significantly different