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Table 4 Oxidative stress

From: Dietary canolol protects the heart against the deleterious effects induced by the association of rapeseed oil, vitamin E and coenzyme Q10 in the context of a high-fat diet

 

C

PS

R

RTC

RTCC

Thiols

55 ± 1a

57 ± 1a

64 ± 1b

62 ± 2b

65 ± 1b

TBARS

0.29 ± 0.01a

0.23 ± 0.01b

0.23 ± 0.02b

0.24 ± 0.02b

0.24 ± 0.01b

FRAP

107 ± 4a

96 ± 3c

88 ± 2cb

88 ± 3cb

86 ± 3b

SOD activity

358 ± 55a

170 ± 20b

167 ± 15b

158 ± 11b

132 ± 21b

GPX activity

1062 ± 22a

1065 ± 28a

1066 ± 26a

1160 ± 25b

1096 ± 26ab

SOD2

0.41 ± 0.03a

0.55 ± 0.09a

0.57 ± 0.08a

0.83 ± 0.10b

0.57 ± 0.08a

GPX4

0.54 ± 0.01a

0.59 ± 0.02ab

0.55 ± 0.03a

0.66 ± 0.04b

0.64 ± 0.04b

Cat

0.30 ± 0.05a

0.51 ± 0.11ab

0.57 ± 0.09ab

0.79 ± 0.15b

0.56 ± 0.11ab

  1. C control rats, PS rats fed a palm oil/sunflower oil mixture, R rats fed rapeseed oil, RTC rats fed rapeseed oil enriched with α-tocopherol and coenzyme Q10, RTCC rats fed RTC plus canolol, TBARS thiobarbituric acid reactive substances, FRAP ferric reducing antioxidant power, SOD superoxide dismutase, GPX glutathione peroxidase, SOD2, GPX4 and Cat SOD2, GPX4 and catalase mRNA expression. Thiols, TBARS and FRAP are expressed in μmoles/g of proteins. SOD and GPX activities are expressed in in U/g of proteins. Averages of 12 rats per group
  2. a, b, cmeans in a row without a common letter are significantly different