Skip to main content

Advertisement

Table 6 Summary of the main significant results

From: Dietary canolol protects the heart against the deleterious effects induced by the association of rapeseed oil, vitamin E and coenzyme Q10 in the context of a high-fat diet

  PS vs. C R vs. PS RTC vs. R RTCC vs. RTC
PL PUFA
 ω6 PUFAs ↓ 18:2 and ↑ 20:4, C22:4, C22:5; ↑ 18:2, ↓ 20:4, 22:4 and 22:5; - -
 ω3 PUFAs ↑ 18:3, 22:5 and 22:6 - -
 PUFAs/SFAs - -
Ag2 pathway
 mRNA Ag2R-1b - -
 Collagen - -
Metabolism
 mRNA for PDK4 - -
 DG - -
 TG - - -
Oxidative stress
 Thiol group - - -
 TBARS - - -
 FRAP - - -
 SOD activity - - -
 GPX activity - - -
 mRNA for SOD2 - -
 mRNA for GPX4 - - -
Apoptosis
 Cleaved caspase-3 - - -
 p53 mRNA - - -
  1. PS vs. C comparison between rats fed the high-saturated fatty acid diet and rats fed the control diet, R vs. PS influence of rapeseed oil in the context of a high-fat diet, RTC vs. R influence of the combination of vitamin E and coenzyme Q10 in the context of a high-fat diet enriched with rapeseed oil, RTCC vs. RTC influence of canolol in the context of a high-fat diet enriched with rapeseed oil, vitamin E and coenzyme Q10, PL phospholipid, PUFAs polyunsaturated fatty acids, SFAs saturated fatty acids, Ag2 angiotensin 2, mRNA messenger ribonucleic acid, PDK4 pyruvate dehydrogenase kinase-4, DG diglyceride, TG triglyceride, TBARS thiobarbituric acid reactive substances, FRAP ferric reducing ability of plasma, SOD superoxide dismutase, GPX glutathione peroxidase