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Table 6 Summary of the main significant results

From: Dietary canolol protects the heart against the deleterious effects induced by the association of rapeseed oil, vitamin E and coenzyme Q10 in the context of a high-fat diet

 

PS vs. C

R vs. PS

RTC vs. R

RTCC vs. RTC

PL PUFA

 ω6 PUFAs

↓ 18:2 and ↑ 20:4, C22:4, C22:5;

↑ 18:2, ↓ 20:4, 22:4 and 22:5;

-

-

 ω3 PUFAs

↑ 18:3, 22:5 and 22:6

-

-

 PUFAs/SFAs

-

-

Ag2 pathway

 mRNA Ag2R-1b

-

-

 Collagen

-

-

Metabolism

 mRNA for PDK4

-

-

 DG

-

-

 TG

-

-

-

Oxidative stress

 Thiol group

-

-

-

 TBARS

-

-

-

 FRAP

-

-

-

 SOD activity

-

-

-

 GPX activity

-

-

-

 mRNA for SOD2

-

-

 mRNA for GPX4

-

-

-

Apoptosis

 Cleaved caspase-3

-

-

-

 p53 mRNA

-

-

-

  1. PS vs. C comparison between rats fed the high-saturated fatty acid diet and rats fed the control diet, R vs. PS influence of rapeseed oil in the context of a high-fat diet, RTC vs. R influence of the combination of vitamin E and coenzyme Q10 in the context of a high-fat diet enriched with rapeseed oil, RTCC vs. RTC influence of canolol in the context of a high-fat diet enriched with rapeseed oil, vitamin E and coenzyme Q10, PL phospholipid, PUFAs polyunsaturated fatty acids, SFAs saturated fatty acids, Ag2 angiotensin 2, mRNA messenger ribonucleic acid, PDK4 pyruvate dehydrogenase kinase-4, DG diglyceride, TG triglyceride, TBARS thiobarbituric acid reactive substances, FRAP ferric reducing ability of plasma, SOD superoxide dismutase, GPX glutathione peroxidase