Energy restriction, exercise and atorvastatin treatment improve endothelial dysfunction and inhibit miRNA-155 in the erectile tissue of the aged rat.

Table 1 Body weight, blood pressure and biochemical determinations in blood

	C	HF	HF/ER	HF/ER/S	HF/ER/S/Ex
Final body weight (g)	748.6 ± 33.8	888.8 ± 91.4	681.6 ± 16.1	584.4 ± 8.3^*,#,+	605.6 ± 15.2^*,+
Systolic blood pressure (mmHg)	104.2 ± 2.0	128.6 ± 1.5	133.5 ± 6.3	130.3 ± 7.2^*	104.6 ± 1.3^#,+,$
Diastolic blood pressure (mmHg)	90.8 ± 3.4	103.6 ± 2.2	83.5 ± 5.6	79.3 ± 2.3^#	82.8 ± 8.2
Glycemia (mg/dL)	105.2 ± 12.4	135.8 ± 5.4	111.0 ± 5.7^#	129.5 ± 5.7	94.0 ± 2.8^#
Total cholesterol (mg/dL)	104.0 ± 13.6	167.4 ± 20.3^*	161.5 ± 12.9^*	124.5 ± 10.4⁺	88.2 ± 9.5^#,+
HDL-c (mg/dL)	62.4 ± 7.5	85.4 ± 8.6	82.8 ± 4.3^*	46.0 ± 10.8^#,+	46.8 ± 5.4^#,+
LDL-c (mg/dL)	28.0 ± 11.0	40.6 ± 8.3	51.8 ± 10.7	33.3 ± 5.5	38.6 ± 3.1
Triglycerides (mg/dL)	155.3 ± 27.3	207.2 ± 40.8	150.0 ± 16.4	106.8 ± 4.6^*,#	71.0 ± 5.2^#,+,$
CRP (mg/L)	3.6 ± 0.5	8.4 ± 1.0^*	3.6 ± 1.1^#	1.8 ± 0.2^*,#,+	2.4 ± 0.1^*,#

Data are presented as mean ± SEM. Data relative to groups C, HF and HF/ER were previously published [7]
C: controls; HF: high-fat; HF/ER: high fat/energy restriction; HF/ER/S: high-fat/energy restriction/statin;: high-fat/energy restriction/statin/exercise
^*p < 0.05 vs C, ^# p < 0.05 vs HF, ⁺ p < 0.05 vs HF/ER, ^$p < 0.05 vs HF/ER/S

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