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Table 2 Association of the PPP1R3B genotypes and serum lipid levels in controls

From: Association between the PPP1R3B polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke in a southern Chinese Han population

Genotype n TC
(mmol/L)
TG
(mmol/L)
HDL-C
(mmol/L)
LDL-C
(mmol/L)
ApoA1
(g/L)
ApoB
(g/L)
ApoA1/
ApoB
rs12785
 TT 356 4.88 ± 1.02 1.25 (0.89) 1.89 ± 0.48 2.79 ± 0.80 1.41 ± 0.26 0.90 ± 0.22 1.66 ± 0.56
 TA 222 4.89 ± 0.87 1.21 (0.68) 1.92 ± 0.49 2.69 ± 0.72 1.4 1 ± 0.23 0.91 ± 0.23 1.64 ± 0.47
 AA 39 4.47 ± 1.05 1.05 (0.82) 1.87 ± 0.52 2.41 ± 0.71 1.34 ± 0.30 0.88 ± 0.24 1.59 ± 0.41
P   0.036 0.320 0.623 0.010 0.231 0.798 0.714
 TT 356 4.88 ± 1.02 1.25 (0.89) 1.89 ± 0.48 2.79 ± 0.80 1.41 ± 0.26 0.90 ± 0.22 1.66 ± 0.56
 TA + AA 261 4.83 ± 0.91 1.19 (0.70) 1.92 ± 0.50 2.65 ± 0.81 1.40 ± 0.24 0.90 ± 0.23 1.63 ± 0.46
P   0.036 0.119 0.610 0.011 0.398 0.560 0.089
rs330910
 AA 396 4.86 ± 1.04 1.26 (0.87) 1.87 ± 0.48 2.77 ± 0.83 1.41 ± 0.26 0.91 ± 0.23 1.65 ± 0.55
 AT 194 4.88 ± 0.86 1.18 (0.62) 1.95 ± 0.51 2.67 ± 0.66 1.42 ± 0.24 0.90 ± 0.22 1.66 ± 0.46
 TT 27 4.64 ± 0.85 1.14 (0.95) 1.92 ± 0.43 2.50 ± 0.59 1.34 ± 0.19 0.93 ± 0.21 1.52 ± 0.40
P   0.522 0.492 0.171 0.092 0.381 0.730 0.416
 AA 396 4.86 ± 1.04 1.26 (0.87) 1.87 ± 0.48 2.77 ± 0.83 1.41 ± 0.26 0.91 ± 0.23 1.65 ± 0.55
 AT+TT 221 4.84 ± 0.86 1.17 (0.67) 1.95 ± 0.50 2.64 ± 0.65 1.41 ± 0.23 0.90 ± 0.22 1.64 ± 0.45
P   0.014 0.064 0.383 0.000 0.299 0.518 0.170
rs330915
 AA 409 4.89 ± 1.00 1.25 (0.85) 1.90 ± 0.48 2.77 ± 0.78 1.42 ± 0.26 0.90 ± 0.22 1.66 ± 0.54
 AT 187 4.86 ± 0.87 1.22 (0.73) 1.92 ± 0.48 2.70 ± 0.74 1.40 ± 0.22 0.91 ± 0.26 1.62 ± 0.48
 TT 21 4.16 ± 1.19 0.85 (0.37) 1.78 ± 0.59 2.24 ± 0.79 1.30 ± 0.37 0.80 ± 0.22 1.65 ± 0.38
P   0.003 0.080 0.488 0.009 0.119 0.095 0.765
 AA 409 4.89 ± 1.00 1.25 (0.85) 1.90 ± 0.48 2.77 ± 0.78 1.42 ± 0.26 0.90 ± 0.22 1.66 ± 0.54
 AT+TT 208 4.79 ± 0.93 1.18 (0.71) 1.91 ± 0.50 2.65 ± 0.75 1.39 ± 0.24 0.90 ± 0.25 1.63 ± 0.47
P   0.172 0.232 0.753 0.325 0.531 0.744 0.266
rs9949
 GG 357 4.87 ± 1.02 1.25 (0.87) 1.89 ± 0.48 2.79 ± 0.80 1.41 ± 0.26 0.90 ± 0.22 1.66 ± 0.55
 GA 222 4.89 ± 0.87 1.22 (0.68) 1.92 ± 0.49 2.69 ± 0.72 1.41 ± 0.23 0.91 ± 0.23 1.64 ± 0.47
 AA 38 4.47 ± 1.07 1.06 (0.80) 1.88 ± 0.53 2.40 ± 0.72 1.34 ± 0.30 0.88 ± 0.25 1.58 ± 0.41
P   0.043 0.354 0.695 0.010 0.182 0.783 0.705
 GG 357 4.87 ± 1.02 1.25 (0.87) 1.89 ± 0.48 2.79 ± 0.80 1.41 ± 0.26 0.90 ± 0.22 1.66 ± 0.55
 GA + AA 260 4.82 ± 0.91 1.19 (0.70) 1.01 ± 0.50 2.65 ± 0.73 1.40 ± 0.24 0.90 ± 0.23 1.63 ± 0.46
P   0.044 0.126 0.585 0.011 0.401 0.594 0.104
  1. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-denstity lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B. The value of triglyceride was presented as median (interquartile range), and the difference among or between the genotypes was determined by the Kruskal-Wallis test or Wilcoxon-Mann-Whitney test. A P < 0.0014 was considered statistically significant after Bonferroni correction