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Table 2 Association of the PPP1R3B genotypes and serum lipid levels in controls

From: Association between the PPP1R3B polymorphisms and serum lipid traits, the risk of coronary artery disease and ischemic stroke in a southern Chinese Han population

Genotype

n

TC

(mmol/L)

TG

(mmol/L)

HDL-C

(mmol/L)

LDL-C

(mmol/L)

ApoA1

(g/L)

ApoB

(g/L)

ApoA1/

ApoB

rs12785

 TT

356

4.88 ± 1.02

1.25 (0.89)

1.89 ± 0.48

2.79 ± 0.80

1.41 ± 0.26

0.90 ± 0.22

1.66 ± 0.56

 TA

222

4.89 ± 0.87

1.21 (0.68)

1.92 ± 0.49

2.69 ± 0.72

1.4 1 ± 0.23

0.91 ± 0.23

1.64 ± 0.47

 AA

39

4.47 ± 1.05

1.05 (0.82)

1.87 ± 0.52

2.41 ± 0.71

1.34 ± 0.30

0.88 ± 0.24

1.59 ± 0.41

 P

 

0.036

0.320

0.623

0.010

0.231

0.798

0.714

 TT

356

4.88 ± 1.02

1.25 (0.89)

1.89 ± 0.48

2.79 ± 0.80

1.41 ± 0.26

0.90 ± 0.22

1.66 ± 0.56

 TA + AA

261

4.83 ± 0.91

1.19 (0.70)

1.92 ± 0.50

2.65 ± 0.81

1.40 ± 0.24

0.90 ± 0.23

1.63 ± 0.46

 P

 

0.036

0.119

0.610

0.011

0.398

0.560

0.089

rs330910

 AA

396

4.86 ± 1.04

1.26 (0.87)

1.87 ± 0.48

2.77 ± 0.83

1.41 ± 0.26

0.91 ± 0.23

1.65 ± 0.55

 AT

194

4.88 ± 0.86

1.18 (0.62)

1.95 ± 0.51

2.67 ± 0.66

1.42 ± 0.24

0.90 ± 0.22

1.66 ± 0.46

 TT

27

4.64 ± 0.85

1.14 (0.95)

1.92 ± 0.43

2.50 ± 0.59

1.34 ± 0.19

0.93 ± 0.21

1.52 ± 0.40

 P

 

0.522

0.492

0.171

0.092

0.381

0.730

0.416

 AA

396

4.86 ± 1.04

1.26 (0.87)

1.87 ± 0.48

2.77 ± 0.83

1.41 ± 0.26

0.91 ± 0.23

1.65 ± 0.55

 AT+TT

221

4.84 ± 0.86

1.17 (0.67)

1.95 ± 0.50

2.64 ± 0.65

1.41 ± 0.23

0.90 ± 0.22

1.64 ± 0.45

 P

 

0.014

0.064

0.383

0.000

0.299

0.518

0.170

rs330915

 AA

409

4.89 ± 1.00

1.25 (0.85)

1.90 ± 0.48

2.77 ± 0.78

1.42 ± 0.26

0.90 ± 0.22

1.66 ± 0.54

 AT

187

4.86 ± 0.87

1.22 (0.73)

1.92 ± 0.48

2.70 ± 0.74

1.40 ± 0.22

0.91 ± 0.26

1.62 ± 0.48

 TT

21

4.16 ± 1.19

0.85 (0.37)

1.78 ± 0.59

2.24 ± 0.79

1.30 ± 0.37

0.80 ± 0.22

1.65 ± 0.38

 P

 

0.003

0.080

0.488

0.009

0.119

0.095

0.765

 AA

409

4.89 ± 1.00

1.25 (0.85)

1.90 ± 0.48

2.77 ± 0.78

1.42 ± 0.26

0.90 ± 0.22

1.66 ± 0.54

 AT+TT

208

4.79 ± 0.93

1.18 (0.71)

1.91 ± 0.50

2.65 ± 0.75

1.39 ± 0.24

0.90 ± 0.25

1.63 ± 0.47

 P

 

0.172

0.232

0.753

0.325

0.531

0.744

0.266

rs9949

 GG

357

4.87 ± 1.02

1.25 (0.87)

1.89 ± 0.48

2.79 ± 0.80

1.41 ± 0.26

0.90 ± 0.22

1.66 ± 0.55

 GA

222

4.89 ± 0.87

1.22 (0.68)

1.92 ± 0.49

2.69 ± 0.72

1.41 ± 0.23

0.91 ± 0.23

1.64 ± 0.47

 AA

38

4.47 ± 1.07

1.06 (0.80)

1.88 ± 0.53

2.40 ± 0.72

1.34 ± 0.30

0.88 ± 0.25

1.58 ± 0.41

 P

 

0.043

0.354

0.695

0.010

0.182

0.783

0.705

 GG

357

4.87 ± 1.02

1.25 (0.87)

1.89 ± 0.48

2.79 ± 0.80

1.41 ± 0.26

0.90 ± 0.22

1.66 ± 0.55

 GA + AA

260

4.82 ± 0.91

1.19 (0.70)

1.01 ± 0.50

2.65 ± 0.73

1.40 ± 0.24

0.90 ± 0.23

1.63 ± 0.46

 P

 

0.044

0.126

0.585

0.011

0.401

0.594

0.104

  1. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-denstity lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B. The value of triglyceride was presented as median (interquartile range), and the difference among or between the genotypes was determined by the Kruskal-Wallis test or Wilcoxon-Mann-Whitney test. A P < 0.0014 was considered statistically significant after Bonferroni correction
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Nutrition & Metabolism

ISSN: 1743-7075

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