Table 7 The Papp values of CA across Caco-2 monolayers treated with various fatty acids and the TEER values (n = 5)

 Vehicle

+

+

+

+

+

 CA

+

+

+

+

+

 C8:0

+

–

–

–

–

 C10:0

–

+

–

–

–

 C18:0

–

–

+

–

–

 C18:1

–

–

–

+

–

 0 μmol/L

P _app ^e

–

–

–

–

1.16 ± 0.14

TEER^f

622.80 ± 56.03

 50 μmol/L

P _app ^e

0.87 ± 0.06^a,c,d

0.93 ± 0.13^a,c

1.26 ± 0.19

1.06 ± 0.02

–

TEER^f

669.80 ± 44.56

713.60 ± 87.06

653.40 ± 59.08

696.60 ± 116.57

 100 μmol/L

P _app ^e

0.74 ± 0.03^a,c,d

0.81 ± 0.06^a,c,d

1.06 ± 0.21

1.1 ± 0.09

–

TEER^f

710.60 ± 115.01

673.80 ± 60.20

628.40 ± 58.92

668.00 ± 124.00

 200 μmol/L

P _app ^e

0.43 ± 0.07^a,b,c,d

0.64 ± 0.04^a,c,d

1.11 ± 0.16

1.02 ± 0.09

–

TEER^f

707.00 ± 134.62

591.20 ± 47.56

651.00 ± 57.72

586.20 ± 53.60