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Fig. 3 | Nutrition & Metabolism

Fig. 3

From: Very low-carbohydrate, high-fat, weight reduction diet decreases hepatic gene response to glucose in obese rats

Fig. 3

Effect of glucose on gene expression in rats consuming LF vs. HF1 diets. Liver samples were obtained from rats consuming either an LF (N = 8) or an HF (N = 10) ad libitum for ten weeks (Phase 1) feed-deprived 16 h (dark bars) and 3 h post-glucose (light bars). Relative hepatic gene expression is plotted as 2-dCt. Means ± SEM are shown; labelled means, for a given gene and condition, without a common letter differ from each other, p < 0.05. *Different from Feed-deprived, p < 0.05. Acaca: acetyl-CoA carboxylase; Fasn: fatty acid synthase; Gck: glucokinase; Insig2: insulin signaling protein 2; Pck1: phosphoenolpyruvate carboxykinase; Scd1: stearoyl-CoA desaturase-1; Srebf1: Sterol regulatory element-binding protein 1. LF, lower-fat; HF1 high-fat Phase 1

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Nutrition & Metabolism

ISSN: 1743-7075

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