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Fig. 3 | Nutrition & Metabolism

Fig. 3

From: α-Tocopherol influences glycaemic control and miR-9-3 DNA methylation in overweight and obese women under an energy-restricted diet: a randomized, double-blind, exploratory, controlled clinical trial

Fig. 3

Effect of α-tocopherol supplementation on miR-9-3 methylation levels. VE: Vitamin E. The synthetic VE contains all-rac-α-tocopherol and contains natural RRR-α-tocopherol. Methylation levels were significantly higher in the natural vitamin E (VE) group after intervention (p = 0.000; adjusted p = 0.000). There were no differences in methylation levels before and after intervention for the synthetic vitamin E group (p = 0.388; adjusted p = 0.776), placebo (p = 0.179; adjusted p = 0.537) and non-intervention group (p = 1.000; adjusted p = 1.000) (paired Wilcoxon test). Adjusted p means that the p-value was corrected by Hommel procedure (modified Bonferroni test)

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Nutrition & Metabolism

ISSN: 1743-7075

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