Long-term high-protein diet intake reverts weight gain and attenuates metabolic dysfunction on high-sucrose-fed adult rats

Table 2 Biochemical profile of hepatic function after nutritional intervention

Biochemical profile of hepatic function	CT/CT	HS/HS	HS/CT	HS/HP
AST (U/L)	27.34 ± 3.58	35.99 ± 3.66	29.04 ± 2.24	30.95 ± 4.59
ALT (U/L)	18.03 ± 0.81	30.94 ± 4.88^a,c,d	16.83 ± 1.41	17.69 ± 1.19
γ-GT (U/L)	21.52 ± 0.52	19.62 ± 1.04	21.75 ± 0.3	22.96 ± 0.28
Alkaline phosphatase (U/L)	26.93 ± 1.77	31.48 ± 3.42	34.59 ± 2.76	32.84 ± 2.47
Albumin (g/dL)	2.43 ± 0.06	2.56 ± 0.09	2.46 ± 0.08	2.35 ± 0.09
Total protein (g/dL)	2.54 ± 0.05	2.67 ± 0.05	2.59 ± 0.02	2.68 ± 0.04
Urea (mg/dL)	48.34 ± 2.58	44.83 ± 3.45	51.42 ± 0.85	51.41 ± 2.21

CT/CT rats fed a standard chow (n = 7), HS/HS rats fed a high-sucrose diet (n = 6), HS/CT rats initially fed HSD and then replaced by standard chow (n = 6); and HS/HP rats fed a HS diet and then replaced by high-protein diet (n = 6). Values represent mean ± SEM, compared by one-way ANOVA (Newman Keuls)
^arepresents p < 0.05 when compared to CT/CT
^crepresents p < 0.05 when compared to HS/CT
^drepresents p < 0.05 when compared to HS/HP

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