Fig. 4From: PPARγ/Pgc-1α-Fndc5 pathway up-regulation in gastrocnemius and heart muscle of exercised, branched chain amino acid diet fed miceEndurance capacity and coordination function in treated groups compare with Sed group. (a) Rotarod performance was applied for each group (n = 6) and the mean of score for each group is shown as mean ± SEM (Standard Error of Mean). Exercise performance and BCAAs supplementation significantly improved rotarod performance (p < 0.05). However simultaneous application of performance and BCAAs supplementation did not exert additive effect on performance. S stands for second. (b) Time to reach exhaustion was measured in trained groups vs sedentary control group. Of important, exercised group supplemented with 20BCAA reached to maximal endurance capacity. + indicates statistically significant difference with Sed group at p < 0.05, * indicates statistically significant difference with 20BCAA/Ex group at p < 0.05, # indicates statistically significant difference with 60BCAA/Ex group at p < 0.05, & indicates statistically significant difference with Ex group at p < 0.05, $ indicates statistically significant difference with 20BCAA group at p < 0.05, ^ indicates statistically significant difference with 60BCAA group at p < 0.05. Data were analyzed by two-way analysis of variance (ANOVA) and tukey’s post hoc testBack to article page