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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: PPARγ/Pgc-1α-Fndc5 pathway up-regulation in gastrocnemius and heart muscle of exercised, branched chain amino acid diet fed mice

Fig. 4

Endurance capacity and coordination function in treated groups compare with Sed group. (a) Rotarod performance was applied for each group (n = 6) and the mean of score for each group is shown as mean ± SEM (Standard Error of Mean). Exercise performance and BCAAs supplementation significantly improved rotarod performance (p < 0.05). However simultaneous application of performance and BCAAs supplementation did not exert additive effect on performance. S stands for second. (b) Time to reach exhaustion was measured in trained groups vs sedentary control group. Of important, exercised group supplemented with 20BCAA reached to maximal endurance capacity. + indicates statistically significant difference with Sed group at p < 0.05, * indicates statistically significant difference with 20BCAA/Ex group at p < 0.05, # indicates statistically significant difference with 60BCAA/Ex group at p < 0.05, & indicates statistically significant difference with Ex group at p < 0.05, $ indicates statistically significant difference with 20BCAA group at p < 0.05, ^ indicates statistically significant difference with 60BCAA group at p < 0.05. Data were analyzed by two-way analysis of variance (ANOVA) and tukey’s post hoc test

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