| REG (n = 30) | RED (n = 26) | CHO (n = 29) | REG vs. RED | REG vs. CHO | |||
---|---|---|---|---|---|---|---|---|
Week 12 | Change from baseline | Week 12 | Change from baseline | Week 12 | Change from baseline | P | P | |
VLDL-P (nmol/l)2 | 148.4 ± 14.1 | − 3.6 ± 15.3 | 129.5 ± 9.4 | −6.0 ± 8.8 | 126.1 ± 13.8 | 3.4 ± 6.7 | 0.56 | 0.67 |
IDL-P (nmol/L) | 73.3 ± 6.9 | − 4.5 ± 6.9 | 68.5 ± 6.5 | − 6.1 ± 5.0 | 68.2 ± 7.0 | 2.1 ± 4.3 | 0.62 | 0.81 |
LDL-P (nmol/l) | ||||||||
 Total | 1322 ± 60.0 | 26.2 ± 41.3 | 1265 ± 78.8 | 7.9 ± 50.2 | 1363 ± 55.5 | − 2.9 ± 39.1 | 0.43 | 0.99 |
 LDL1 + 2b | 415.9 ± 21.4 | 22.2 ± 15.1 | 444.2 ± 23.0 | − 13.3 ± 19.3 | 453.2 ± 22.4 | −29.3 ± 14.7 | 0.82 | 0.16 |
 LDL3 + 4b | 403.2 ± 20.6 | 9.9 ± 22.4 | 414.9 ± 31.6 | 15.9 ± 19.5 | 403.3 ± 22.2 | − 10.8 ± 18.1 | 0.98 | 0.76 |
 LDL5 + 6b | 487.7 ± 43.1 | − 12.7 ± 20.5 | 391.1 ± 43.6 | −7.7 ± 25.7 | 479.6 ± 49.3 | 32.0 ± 19.0 | 0.39 | 0.35 |
VLDL-C (mg/dl) | ||||||||
 Totalb | 16.5 ± 2.2 | −0.5 ± 2.4 | 13.2 ± 1.6 | −1.3 ± 1.3 | 12.8 ± 2.4 | 0.7 ± 1.2 | 0.47 | 0.68 |
 VLDL1 + 2 | 7.3 ± 1.2 | 0.7 ± 1.1 | 4.9 ± 0.9 | − 0.5 ± 0.6 | 5.0 ± 1.3 | 0.1 ± 0.1 | 0.26 | 0.56 |
 VLDL3 + 4b | 6.7 ± 1.0 | − 1.2 ± 1.3 | 5.6 ± 0.7 | −1.0 ± 0.7 | 5.4 ± 1.0 | − 0.2 ± 0.5 | 0.67 | 0.87 |
 VLDL5 + 6b | 2.1 ± 0.1 | − 0.1 ± 0.1 | 2.0 ± 0.1 | 0.0 ± 0.1 | 2.0 ± 0.1 | 0.7 ± 0.7 | 0.96 | 0.68 |
 IDL-C (mg/dl) | 7.0 ± 1.1 | − 0.2 ± 0.9 | 6.7 ± 1.1 | −1.5 ± 1.3 | 7.1 ± 1.3 | 0.1 ± 0.7 | 0.28 | 0.81 |
LDL-C (mg/dl) | ||||||||
 Total | 118.2 ± 5.4 | 3.7 ± 4.4 | 117.3 ± 7.3 | 3.8 ± 4.9 | 122.6 ± 4.5 | −2.6 ± 3.9 | 0.69 | 0.70 |
 LDL1 + 2b | 42.8 ± 2.5 | 2.7 ± 1.7 | 46.6 ± 2.6 | −0.5 ± 2.3 | 47.2 ± 2.4 | −3.2 ± 1.9 | 0.51 | 0.19 |
 LDL3 + 4b | 38.2 ± 2.2 | 0.9 ± 2.1 | 40.0 ± 3.1 | 2.3 ± 2.1 | 38.7 ± 2.2 | −1.7 ± 1.8 | 0.72 | 0.57 |
 LDL5 + 6b | 36.2 ± 3.1 | − 0.5 ± 1.4 | 29.6 ± 3.4 | 0.2 ± 2.0 | 35.7 ± 3.5 | 2.1 ± 1.5 | 0.88 | 0.21 |
HDL-C (mg/dl) | ||||||||
 Total | 56.0 ± 2.9 | 2.2 ± 1.0 | 56.5 ± 2.5 | 2.4 ± 1.3 | 55.9 ± 2.3 | − 0.6 ± 1.3 | 0.84 | 0.03 |
 HDL1 + 2b | 27.1 ± 2.7 | 1.0 ± 0.8 | 27.5 ± 2.1 | 0.6 ± 1.0 | 28.6 ± 2.0 | 0.1 ± 1.1 | 0.68 | 0.23 |
 HDL3 + 4b | 29.4 ± 0.8 | 1.2 ± 0.6 | 29.4 ± 0.9 | 1.6 ± 0.7 | 27.8 ± 0.9 | − 0.8 ± 0.6 | 0.95 | 0.02 |
 LDL-C:HDL-C ratio | 2.2 ± 0.1 | 0.0 ± 0.1 | 2.2 ± 0.2 | 0.0 ± 0.1 | 2.3 ± 0.1 | 0.0 ± 0.1 | 0.62 | 0.81 |
 Apo-B:Apo-A1 ratio | 0.6 ± 0.0 | 0.0 ± 0.0 | 0.6 ± 0.0 | 0.0 ± 0.1 | 0.7 ± 0.0 | 0.0 ± 0.0 | 0.67 | 0.16 |