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Table 1 Body composition, absolute and relative heart weight

From: Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity

 

SD n = 7

FFC n = 14

FFC/SD n = 14

Overall P value

BW (kg)

 Mid-study

31.0 (30.0–32.0)

50.0 (47.0–55.0)***

49.5 (47.0–54.0)***

0.0003

 Termination

39.0 (38.0–41.0)

78.0 (69.0–81.0)***

55.0 (51.0–59.0)***††††

<.0001

Fat percentage (%)

 Mid-study

20.5 (18.5–26.3)

40.2 (37.6–41.9)***

41.6 (38.8–44.5)***

0.0001

 Termination

27.6 (24.0–30.7)

64.2 (61.4–67.6)***

47.3 (41.2–50.2)***††††

<.0001

LBM (kg)

 Mid-study

22.8 (20.1–23.1)

27.1 (25.0–28.2)**

25.6 (24.4–26.3)**

0.002

 Termination

26.9 (24.0–28.6)

27.0 (24.8–27.8)

29.5 (27.3–30.5)

0.2

HW (g)

 Termination

131 (115–142)

199 (181–208)a***

173 (168–180)***

<.0001

HW/BW (g/kg)

 Termination

3.3 (3.1–3.4)

2.6 (2.5–2.8)a***

3.3 (3.0–3.4)††††

<.0001

HW/LBM (g/kg)

 Termination

5.0 (4.2–5.2)

7.7 (6.8–8.2)a***

6.2 (5.9–6.7)***†††

<.0001

  1. Data is presented as median and interquartile range (25th–75th)
  2. SD fed standard chow, FFC fed fat/fructose/cholesterol-rich diet, FFC/SD dietary normalization, BW body weight, LBM lean body mass, HW heart weight
  3. **P < 0.01; ***P < 0.001, significantly different from SD, †††P < 0.001; ††††P < 0.0001, significantly different from FFC
  4. a n = 13