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Table 1 Body composition, absolute and relative heart weight

From: Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity

  SD n = 7 FFC n = 14 FFC/SD n = 14 Overall P value
BW (kg)
 Mid-study 31.0 (30.0–32.0) 50.0 (47.0–55.0)*** 49.5 (47.0–54.0)*** 0.0003
 Termination 39.0 (38.0–41.0) 78.0 (69.0–81.0)*** 55.0 (51.0–59.0)***†††† <.0001
Fat percentage (%)
 Mid-study 20.5 (18.5–26.3) 40.2 (37.6–41.9)*** 41.6 (38.8–44.5)*** 0.0001
 Termination 27.6 (24.0–30.7) 64.2 (61.4–67.6)*** 47.3 (41.2–50.2)***†††† <.0001
LBM (kg)
 Mid-study 22.8 (20.1–23.1) 27.1 (25.0–28.2)** 25.6 (24.4–26.3)** 0.002
 Termination 26.9 (24.0–28.6) 27.0 (24.8–27.8) 29.5 (27.3–30.5) 0.2
HW (g)
 Termination 131 (115–142) 199 (181–208)a*** 173 (168–180)*** <.0001
HW/BW (g/kg)
 Termination 3.3 (3.1–3.4) 2.6 (2.5–2.8)a*** 3.3 (3.0–3.4)†††† <.0001
HW/LBM (g/kg)
 Termination 5.0 (4.2–5.2) 7.7 (6.8–8.2)a*** 6.2 (5.9–6.7)***††† <.0001
  1. Data is presented as median and interquartile range (25th–75th)
  2. SD fed standard chow, FFC fed fat/fructose/cholesterol-rich diet, FFC/SD dietary normalization, BW body weight, LBM lean body mass, HW heart weight
  3. **P < 0.01; ***P < 0.001, significantly different from SD, †††P < 0.001; ††††P < 0.0001, significantly different from FFC
  4. a n = 13