Table 1 Characteristics of the study population
From: Bariatric surgery reduces CD36-bearing microvesicles of endothelial and monocyte origin
Baseline | 3 monthFollow-up | Δ | P-value | |
|---|---|---|---|---|
(n = 20) | (n = 20) | |||
Age [Years] | 46.5 ± 11.2 | |||
Sex [M/F] | 2/18 | |||
Metabolic Syndrome [n (%)] | 13 (65%) | 2 (10%) | ||
NASH [n (%)] | 13 (65%) | 11 (55%) | ||
Haemoglobin [mmol l−1] | 8.5 ± 0.5 | 8.4 ± 0.6 | −0.1 ± 0.4 | 0.1405 |
Weight [kg] | 118 (108.75; 127) | 94 (84.7; 100) | −23.33 ± 4.21 | 0.0001 |
BMI [kg m− 2] | 42.1 (40.4; 44.1) | 33.9 (32.0; 35.0) | −8.4 ± 1.4 | < 0.0001 |
Total Fat Mass [kg] | 54.8 ± 11.0 | 40.2 (32.9; 42.3) | −15.6 ± 35. 6 | < 0.0001 |
Body Fat Percentage [%] | 45.3 ± 4.9 | 39.4 ± 6.5 | −5.6 ± 2.4 | < 0.0001 |
Fat Mass/Fat Free Mass [AU] | 0.84 ± 0.16 | 0.67 ± 0.17 | −0.16 ± 0.06 | < 0.0001 |
Android Fat [kg] | 48.2 ± 8.2 | 31.9 ± 9.6 | −16.8 ± 4.7 | < 0.0001 |
Android Fat Percentage [%] | 46.8 ± 4.0 | 39.5 ± 6.0 | −7.3 ± 3.8 | < 0.0001 |
Truncal Fat [kg] | 26.6 ± 40.3 | 17.9 ± 49.2 | −8.4 ± 2.9 | < 0.0001 |
Truncal Fat Percentage [%] | 44.5 ± 3.7 | 37.5 ± 6.4 | −6.6 ± 3.9 | < 0.0001 |
Total Cholesterol [mmol l−1] | 4.92 ± 1.00 | 4.49 ± 0.88 | −0.44 ± 0.82 | 0.0275 |
HDL Cholesterol [mmol l−1] | 1.14 ± 0.27 | 1.12 ± 0.28 | −0.02 ± 0.15 | 0.659 |
LDL Cholesterol [mmol l−1] | 2.99 ± 0.87 | 2.82 ± 0.69 | −0.18 ± 0.73 | 0.2992 |
Oxidized LDL Cholesterol | 4.53 ± 1.13 | 4.34 ± 0.93 | −0.19 ± 0.84 | 0.3203 |
Triglycerides [mmol l−1] | 1.72 ± 0.62 | 1.15 (1.05; 1.45) | −0.46 ± 0.52 | 0.001 |
Triglyceride/HDL [AU] | 1.38 (1.09; 1.89) | 1.03 (0.86; 1.41) | −0.41 ± 0.54 | 0.0023 |
Glycated Haemoglobin [%] | 5.9 ± 0.43 | 5.6 (5.5; 5.8) | −0.14 ± 0.40 | 0.0792 |
Fasting Glucose [mmol l−1] | 5.45 (5.18; 6.03) | 5.1 (4.78; 5.33) | −0.45 (− 0.8; − 0.15) | 0.0157 |
Fasting C-Peptide [pmol l− 1] | 1061 (921; 1422) | 745 (566; 935) | − 360 (− 542; −36.3) | 0.0094 |
Fasting Insulin [pmol l− 1] | 131.7 (97.5; 201.5) | 63.7 (53.7; 77.8) | −69.7 (− 105.7; −40.8) | 0.0014 |
HOMAIR | 2.55 (2.05; 3.2) | 1.6 (1.3; 2.05) | −0.85 (− 1.43; − 0.075) | 0.0149 |
HOMASE | 42.7 ± 16.4 | 60.4 ± 20.7 | 17.7 ± 26.3 | 0.0072 |
YKL40 [ng ml−1] | 57.5 (47; 68.3) | 58 (45; 72.8) | 1.1 ± 14.8 | 1 |
Liver Fat Percentage [%] | 6.7 (4.54; 9.99) | 2.82 (2.23; 3.79) | −2.78 (−6.23; −1.84) | 0.0002 |
ALT [U I−1] | 30.9 ± 13.6 | 29.4 ± 15.8 | −1.45 ± 20.4 | 0.7537 |
AST [U I−1] | 28 (25; 32.3) | 26 (22; 37) | 0.65 ± 12.1 | 0.9826 |
AST/ALT [AU] | 0.97 (0.88; 1.36) | 0.97 (0.92; 1.24) | 0.06 (−0.11; 0.30) | 0.33 |
Leukocytes [mia l−1] | 8.37 ± 2.24 | 6.65 (5.73; 8.08) | −1.34 ± 1.15 | 0.0003 |
High-sensitivity CRP [mg l−1] | 4.67 (2.78; 9.99) | 2.16 (1.28; 5.16) | −3.91 ± 6.15 | 0.0073 |
Soluble CD36 [AU] | 0.48 ± 0.20 | 0.37 (0.24; 0.40) | −0.13 (−0.19; − 0.06) | 0.0008 |