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Fig. 11 | Nutrition & Metabolism

Fig. 11

From: Gynura divaricata rich in 3, 5−/4, 5-dicaffeoylquinic acid and chlorogenic acid reduces islet cell apoptosis and improves pancreatic function in type 2 diabetic mice

Fig. 11

Effect of GD on GLUT2, GK, MafA, PDX-1, Bcl-2, Bax, and caspase-3 protein expressions in pancreatic tissues. (A) Western blot analysis of GLUT2, GK, MafA, PDX-1, Bcl-2, Bax, and caspase-3 protein expressions. (B) Quantitative analysis of GLUT2, GK, MafA, and PDX-1 protein expressions. (C) Quantitative analysis of Bcl-2, Bax, and caspase-3 protein expressions. A: normal group; B: diabetic model group; C: 1% GD-treated diabetic group; D: 5% GD-treated diabetic group; E: 10% GD-treated diabetic group. The experimental data are presented as means ± SD. *P < 0.05 and **P < 0.01, respectively, versus normal group; #P < 0.05 and ##P < 0.01, respectively, versus diabetic model group

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