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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: The protective effect of neonatal oral administration of oleanolic acid against the subsequent development of fructose-induced metabolic dysfunction in male and female rats

Fig. 1

Schematic flow diagram showing the experimental groups, stages of development, sequence and timing of interventions and measurements for the experimental study. DW = gavaged daily with 10 mL/kg body mass of distilled water with 0.5% (v/v) dimethyl sulphoxide in the neonatal phase (n = 26; ♀&♂); OA = gavaged daily with 10 mL/kg body mass of oleanolic acid (60 mg/kg) in the neonatal phase (n = 31; ♀&♂); HF = gavaged daily with 10 mL/kg of 20% (w/v) fructose solution in the neonatal phase (n = 28; ♀&♂); OAHF = gavaged daily with 10 mL/kg body mass of oleanolic acid (60 mg/kg) and 20% (w/v) fructose solution in the neonatal period (n = 27; ♀&♂); OGGT = oral glucose tolerance test; GIT = gastrointestinal tract; PD = post-natal day; ♀ = female rats; ♂ = male rats

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