|
Dietary intakes
|
Nanocurcumin (n = 42) Mean(SD)
|
Placebo (n = 42) Mean(SD)
|
P-value
|
|---|
|
Energy (kcal)
|
Baseline
|
2473.2(470.5)
|
2338.6(496.3)
|
0.2*
|
0.001**
|
|
1.5 Months
|
2089.9(412.9)
|
2267.0(468.4)
|
0.07
|
|
3 Months
|
2019.4(380.5)
|
2205.9(476.0)
|
0.05
|
|
Protein (g)
|
Baseline
|
100.7(30.7)
|
97.1(32.7)
|
0.6
|
0.3
|
|
1.5 Months
|
93.7(24.9)
|
93.8(31.8)
|
0.8
|
|
3 Months
|
84.1(28.7)
|
92.9(31.4)
|
0.2
|
|
Protein (%)
|
Baseline
|
16.3(3.7)
|
16.5(4.1)
|
0.7
|
0.2
|
|
1.5 Months
|
18.0(3.8)
|
16.4(3.9)
|
0.06
|
|
3 Months
|
16.6(4.8)
|
16.7(4.1)
|
0.8
|
|
Carbohydrate (g)
|
Baseline
|
296.1(55.6)
|
280.5(81.9)
|
0.3
|
0.3
|
|
1.5 Months
|
253.8(68.9)
|
252.3(58.9)
|
0.9
|
|
3 Months
|
256.2(47.8)
|
266.0(73.3)
|
0.3
|
|
Carbohydrate (%)
|
Baseline
|
48.5(7.7) %
|
47.8(9.0) %
|
0.7
|
0.5
|
|
1.5 Months
|
48.4(8.7) %
|
45.1(8.7) %
|
0.08
|
|
3 Months
|
51.2(7.4) %
|
48.1(8.0) %
|
0.07
|
|
Fat total (g)
|
Baseline
|
103.1(32.8)
|
97.0(27.4)
|
0.3
|
0.001
|
|
1.5 Months
|
82.3(22.5)
|
102.4(31.1)
|
0.001
|
|
3 Months
|
78.7(20.6)
|
90.4(24.6)
|
0.02
|
|
Fat total (%)
|
Baseline
|
37.00(6.9) %
|
37.5(7.4) %
|
0.7
|
0.1
|
|
1.5 Months
|
35.5(6.7) %
|
40.2(7.1) %
|
0.003
|
|
3 Months
|
34.8(4.9) %
|
37.0(6.6) %
|
0.09
|
|
Cholesterol (mg)
|
Baseline
|
268.2(168.8)
|
282.3(178.7)
|
0.7
|
0.3
|
|
1.5 Months
|
273.9(150.8)
|
271.3(153.1)
|
0.9
|
|
3 Months
|
198.3(126.8)
|
263.9(125.6)
|
0.01
|
|
Saturated fat (g)
|
Baseline
|
27.3(11.4)
|
25.5(9.2)
|
0.7
|
0.03
|
|
1.5 Months
|
22.5(7.2)
|
27.9(9.7)
|
0.005
|
|
3 Months
|
21.2(8.5)
|
25.6(9.8)
|
0.03
|
|
Monounsaturated fatty acid (g)
|
Baseline
|
37.8(13.7)
|
36.1(9.8)
|
0.5
|
0.008
|
|
1.5 Months
|
30.4(8.9)
|
36.7(11.6)
|
0.006
|
|
3 Months
|
28.5(8.2)
|
33.7(9.0)
|
0.008
|
|
Polyunsaturated fatty acid (g)
|
Baseline
|
26.4(13.6)
|
25.0(11.6)
|
0.5
|
0.06
|
|
1.5 Months
|
20.3(7.6)
|
26.6(15.3)
|
0.1
|
|
3 Months
|
20.2(6.8)
|
22.1(7.1)
|
0.4
|
|
Vitamin A (RAE) (μg)
|
Baseline
|
316.8(210.7)
|
349.0(264.2)
|
0.6
|
0.6
|
|
1.5 Months
|
366.9(287.1)
|
319.7(270.6)
|
0.2
|
|
3 Months
|
416.2(378.3)
|
407.0(344.8)
|
0.4
|
|
Carotenoids (μg)
|
Baseline
|
8009.3(6994.8)
|
7580.6(6601.1)
|
0.7
|
0.8
|
|
1.5 Months
|
8527.0(6850.7)
|
8068.6(6627.9)
|
0.7
|
|
3 Months
|
8184.9(6718.9)
|
8705.7(7724.2)
|
0.9
|
|
Vitamin C (mg)
|
Baseline
|
97.0(84.4)
|
79.8(61.3)
|
0.4
|
0.9
|
|
1.5 Months
|
83.8(61.0)
|
74.2(69.4)
|
0.1
|
|
3 Months
|
95.1(73.5)
|
85.7(71.8)
|
0.2
|
|
Calcium (mg)
|
Baseline
|
1086.0(502.2)
|
1115.7(521.2)
|
0.7
|
0.1
|
|
1.5 Months
|
1025.8(360.1)
|
910.2(473.1)
|
0.03
|
|
3 Months
|
897.8(408.9)
|
1076.8(475.1)
|
0.06
|
|
Iron (mg)
|
Baseline
|
15.0(3.5)
|
14.8(5.0)
|
0.7
|
0.3
|
|
1.5 Months
|
14.1(4.0)
|
13.7(3.1)
|
0.6
|
|
3 Months
|
13.1(3.1)
|
14.1(4.0)
|
0.1
|
|
Vitamin D (μg)
|
Baseline
|
1.0(1.8)
|
1.9(2.1)
|
0.01
|
0.02
|
|
1.5 Months
|
2.4(3.6)
|
1.1(1.6)
|
0.03
|
|
3 Months
|
2.1(3.5)
|
1.4(1.6)
|
0.9
|
|
Vitamin E (mg)
|
Baseline
|
29.7(19.0)
|
28.7(13.1)
|
0.7
|
0.5
|
|
1.5 Months
|
24.9(9.2)
|
27.0(14.6)
|
0.4
|
|
3 Months
|
23.7(8.6)
|
26.9(8.2)
|
0.1
|
|
Vitamin B1 (mg)
|
Baseline
|
1.9(0.3)
|
1.7(0.5)
|
0.08
|
0.01
|
|
1.5 Months
|
1.6(0.4)
|
1.5(0.4)
|
0.3
|
|
3 Months
|
1.5(0.3)
|
1.7(0.5)
|
0.06
|
|
Vitamin B2 (mg)
|
Baseline
|
1.9(0.7)
|
2.0(0.8)
|
0.5
|
0.1
|
|
1.5 Months
|
1.9(0.6)
|
1.8(0.6)
|
0.1
|
|
3 Months
|
1.7(0.7)
|
1.9(0.7)
|
0.1
|
|
Vitamin B3 (mg)
|
Baseline
|
30.3(13.2)
|
27.8(12.9)
|
0.4
|
0.4
|
|
1.5 Months
|
25.7(10.2)
|
27.2(14.7)
|
0.8
|
|
3 Months
|
24.2(10.6)
|
26.3(11.9)
|
0.4
|
|
Vitamin B6 (mg)
|
Baseline
|
2.2(0.7)
|
1.9(0.6)
|
0.05
|
0.02
|
|
1.5 Months
|
1.8(0.5)
|
1.8(0.7)
|
0.5
|
|
3 Months
|
1.7(0.6)
|
1.9(0.6)
|
0.1
|
|
Folate (DFE) (μg)
|
Baseline
|
504.0(222.7)
|
443.6(181.5)
|
0.3
|
0.04
|
|
1.5 Months
|
425.7(155.8)
|
426.5(149.7)
|
0.7
|
|
3 Months
|
413.0(126.7)
|
471.7(152.9)
|
0.05
|
|
Vitamin B12 (μg)
|
Baseline
|
4.1(2.5)
|
4.4(2.5)
|
0.6
|
0.6
|
|
1.5 Months
|
5.1(2.8)
|
4.6(2.5)
|
0.5
|
|
3 Months
|
4.3(3.0)
|
4.4(2.4)
|
0.9
|
|
Vitamin K (μg)
|
Baseline
|
148.6(224.4)
|
134.9(287.3)
|
0.1
|
0.8
|
|
1.5 Months
|
142.6(279.7)
|
86.5(135.3)
|
0.5
|
|
3 Months
|
192.2(366.3)
|
168.8(419.1)
|
0.6
|
|
Zinc (mg)
|
Baseline
|
12.4(3.3)
|
12.7(3.7)
|
0.7
|
0.7
|
|
1.5 Months
|
12.6(4.0)
|
12.4(3.3)
|
0.7
|
|
3 Months
|
11.5(3.7)
|
12.1(4.5)
|
0.6
|
|
Selenium (μg)
|
Baseline
|
113.7(34.2)
|
119.9(54.1)
|
0.7
|
0.2
|
|
1.5 Months
|
120.4(58.1)
|
99.2(37.9)
|
0.09
|
|
3 Months
|
112.0(57.7)
|
106.6(44.5)
|
0.6
|
|
Fiber total (g)
|
Baseline
|
29.8(12.8)
|
31.0(16.1)
|
0.9
|
0.09
|
|
1.5 Months
|
30.1(16.5)
|
27.1(15.1)
|
0.5
|
|
3 Months
|
24.5(9.5)
|
31.5(15.6)
|
0.03
|
- *Total of the column: t-test or Mann-Whitney; **Total of the column: Two way repeated measures-ANOVA (TWRM-ANOVA)
