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Table 3 Effect of SCLE on the serum biochemical parameters and liver lipid levels in mice

From: Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice

 

Control

HFD

HFD + 0.25% SCLE

HFD + 0.5% SCLE

HFD + 1.0% SCLE

Serum biochemical parameters (mmol/L)

 TC

1.87 ± 0.09c

3.03 ± 0.21a

2.57 ± 0.06ab

2.49 ± 0.16b

2.45 ± 0.13b

 TG

1.49 ± 0.11b

2.53 ± 0.18a

1.40 ± 0.12b

1.42 ± 0.11b

1.57 ± 0.09b

 HDL-C

1.10 ± 0.07b

1.43 ± 0.10b

2.15 ± 0.16a

2.45 ± 0.11a

2.22 ± 0.20a

 LDL-C

0.79 ± 0.05c

1.53 ± 0.08a

1.26 ± 0.05b

1.20 ± 0.14b

1.19 ± 0.08b

Liver lipids (mmol/g liver)

 TC

7.37 ± 0.76b

13.82 ± 0.82a

10.18 ± 0.51b

9.23 ± 0.93b

7.93 ± 0.71b

 TG

22.30 ± 2.55b

33.72 ± 1.37a

28.88 ± 2.96ab

26.79 ± 1.50b

25.44 ± 1.64b

  1. Values are means ± SEM of 10 mice. Means within the same row but not sharing the same superscript letter are significantly different (P < 0.05)
  2. HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TC: total cholesterol; TG, triglyceride