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Table 1 Differential metabolites in response to model group vs. normal group

From: Metabolic effects of mulberry branch bark powder on diabetic mice based on GC-MS metabolomics approach

No

Metabolites

VIP*

t-test P*

FC*

Trend

1

Sophorose

1.948

4.41E-06

2.139

Up

2

Thiogalactopyranoside

1.953

5.43E-06

2.072

Up

3

Glucose

1.711

7.87E-05

2.069

Up

4

Maltose

1.976

1.66E-06

2.054

Up

5

Sorbitol

1.917

1.69E-05

1.988

Up

6

D-(glycerol 1-phosphate)

1.501

0.001135

1.905

Up

7

3,6-Anhydro-D-galactose

1.765

9.95E-06

1.786

Up

8

Fructose

1.078

0.03948

1.758

Up

9

Tagatose

1.763

0.00056

1.728

Up

10

D-Fructose 1,6-bisphosphate

1.879

9.97E-06

0.602

Down

11

Maltotriose

1.315

0.028018

0.507

Down

12

1,5-anhydroglucitol

1.395

0.006196

0.480

Down

13

Sucrose

2.023

0.005275

0.163

Down

14

Erythrose

2.136

7.17E-10

0.103

Down

15

Gluconic lactone

1.403

0.002208

0.071

Down

16

Galactose

1.920

2.88E-05

0.047

Down

17

L-Malic acid

1.590

0.001329

0.656

Down

18

3-hydroxy-3-methylglutaric acid

1.498

0.010145

3.371

Up

19

Palmitoleic acid

1.794

0.000802

2.483

Up

20

Linolenic acid

1.822

7.01E-05

1.501

Up

21

Linoleic acid

1.986

9.87E-08

0.559

Down

22

Linoleic acid methyl ester

1.223

0.006099

0.315

Down

23

Monoolein

1.310

0.000797

0.292

Down

24

Zymosterol

1.023

4.05E-05

0.230

Down

25

Hydrocinnamic acid

1.137

0.006299

0.207

Down

26

Arachidonic acid

1.958

4.18E-05

0.198

Down

27

3-Hydroxyanthranilic acid

1.499

0.023418

2.390

Up

28

Cycloleucine

1.823

0.000221

2.025

Up

29

Glutamine

1.583

0.000371

1.630

Up

30

Methionine

1.610

0.003739

0.634

Down

31

Canavanine

1.117

0.040176

0.625

Down

32

O-phosphonothreonine

1.480

0.002276

0.624

Down

33

4-aminobutyric acid

1.099

0.048405

0.576

Down

34

Citrulline

1.924

7.34E-06

0.495

Down

35

Sarcosine

1.268

0.003764

0.411

Down

36

4-hydroxyphenylethanol

2.078

3.57E-11

3.620

Up

37

Hippuric acid

1.027

0.049162

0.151

Down

38

Taurine

2.074

5.83E-08

0.391

Down

39

O-phosphorylethanolamine

1.829

0.000744

3.523

Up

40

Maleimide

1.361

0.00019

3.055

Up

41

5-Aminoimidazole-4-carboxamide

1.115

0.028222

6.135

Up

42

Inositol

2.169

1.325E-10

0.000

Down

43

Allantoic acid

1.675

0.000228

0.418

Down

44

Kyotorphin

1.245

0.000396

0.294

Down

45

5,6-dihydrouracil

1.213

0.013668

0.045

Down

46

Trans,trans-Muconic acid

1.364

0.029647

0.000

Down

  1. * Variable importance in the projection (VIP) was obtained from OPLS-DA with a threshold of 1.0; P value was calculated from student’s test. Fold change (FC) was calculated from the mean value between Model and Normal group
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Nutrition & Metabolism

ISSN: 1743-7075

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