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Table 4 Effect of PY on plasma lipid profiles over 16 weeks

From: Physcion reduces lipid accumulation and prevents the obesity in mice

 

ND

HFD

PY

FFA (mmol/L)

0.62 ± 0.03

0.73 ± 0.02**

0.68 ± 0.02$

TG (mmol/L)

0.77 ± 0.05

1.10 ± 0.05***

1.10 ± 0.04

Total-C (mmol/L)

3.63 ± 0.11

6.38 ± 0.28***

5.08 ± 0.24$$

HDL-C (mmol/L)

1.68 ± 0.10

3.04 ± 0.09***

2.63 ± 0.14$

nonHDL-C (mmol/L)

1.94 ± 0.12

3.34 ± 0.23***

2.44 ± 0.13$$

Apo B (mg/dL)

4.14 ± 0.37

6.07 ± 0.40**

4.74 ± 0.26$

  1. Data are mean ± S.E. Significant differences between HFD versus ND are indicated; **p < 0.01, ***p < 0.001. Significant differences between HFD and PY are indicated; $p < 0.05, $$p < 0.01. ND, normal diet (AIN-76, 5% fat, w/w); HFD, high-fat diet (20% fat, 1% cholesterol, w/w); PY, HFD + 0.002% physcion (w/w); FFA, free fatty acid; TG, triglyceride; Total-C, total-cholesterol; HDL-C, HDL-cholesterol; nonHDL-C, nonHDL-cholesterol = (Total-C)-(HDL-C); Apo B, apolipoprotein B