Fig. 3

Diet supplemented with blueberry attenuated HFD-induced glucose intolerance and insulin resistance. a Glucose tolerance test (GTT) was performed in 12-wk-old mice fed with HFD or HFD + B after a 16 h fast. Blood glucose levels were determined at baseline and at the indicated times after glucose injection (1.5 g/kg body weight). b The area under the curve (AUC) during GTT. c The plasma insulin was measured at 0, 15 and 30 min after glucose injection (1.5 g/kg body weight). d Insulin tolerance test (ITT) was performed in 14-wk-old mice fed with HFD or HFD + B after a 6 h fast. Blood glucose levels were presented as the percentages of time-course blood glucose levels over the baseline level after intraperitoneal injection of insulin (0.5 U/kg body weight). e The area under the curve (AUC) during ITT. *P < 0.05; **P < 0.01; n = 4–8 mice per group