Fig. 1

Curcumin (CUR) ameliorates obesity in high-fat/high-sugar (HFS) diet-induced obese mice. Control, HFS and HFS + CUR fed mice were measured biweekly for a Body weight (g), b accumulated food intake (g), and c water consumption (mL) (n = 16 per each group). Control, HFS, and HFS + CUR mice were fasted overnight, and blood glucose levels (mg/dL), plasma insulin levels (ng/mL) and HOMA-IR was calculated at 4 weeks (d-f) and at 16 weeks (g-i) of diet. (^*p ≤ 0.05, ^**p ≤ 0.01, ^***p ≤ 0.001, ^****p ≤ 0.0001 compared to Control; ^#p ≤ 0.05, ^##p ≤ 0.01, ^###p ≤ 0.001 compared to HFS + CUR)