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Table 3 Sensitivity and specificity of standard lipid panel measures to identify individuals at greater or lesser risk for worsened sLDL-P

From: Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study

Lipid measure (5% Δ)

≥5% Δ sLDL-P

Sensitivity % [TP/(TP + FN)]; [95% CI]

<5% Δ sLDL-P

Specificity % [(TN/(TN + FP)]; [95% CI]

LDL-C

58.3% (7/12); [27.7, 84.8]

45.0% (18/40); [29.3, 61.5]

Triglyceride/HDL-C Ratio

6/12 (50.0%); [21.1, 78.9]

85.0% (34/40); [70.2, 94.3]

Non-HDL-C Cholesterol

58.3% (7/12); [27.7, 84.8]

60.0% (24/40); [43.3, 75.1]

  1. Note. Δ = Change from baseline to 6 months computed as (6 months minus baseline); TP = true positive, FN = false negative, TN = true negative, FP = false positive