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Table 2 Effect of alcohol and GRSs on blood glucose deterioration

From: Alcohol consumption and its interaction with genetic variants are strongly associated with the risk of type 2 diabetes: a prospective cohort study

 

Overall

Men

Women

 

OR (95% CI)

P-value

OR (95% CI)

P-value

OR (95% CI)

P-value

Alcohol

2.24 (1.76, 2.87)

<.0001*

1.84 (1.20,2.84)

0.0055

2.47 (1.84, 3.32)

0.0032*

T2D-GRS

1.25 (1.11, 1.42)

0.0004*

1.24 (1.03, 1.51)

0.0269

1.26 (1.07, 1.49)

0.0062

BC-GRS

1.04 (0.99, 1.08)

0.0565

1.05 (0.99, 1.11)

0.1384

1.03 (0.98, 1.08)

0.2151

IR-GRS

1.09 (1.01, 1.17)

0.0308

1.17 (1.04, 1.32)

0.009

1.03 (0.94, 1.14)

0.5164

WHR-GRS

1.14 (1.00, 1.30)

0.0439

1.30 (1.06, 1.60)

0.0113

1.05 (0.88,1.24)

0.6032

BMI-GRS

0.92 (0.81, 1.04)

0.1973

0.95 (0.78, 1.15)

0.5693

0.90 (0.76, 1.07)

0.232

  1. Data are shown as odds ratio and 95% confidence intervals
  2. Covariates: age, sex, smoking, and BMI
  3. P values <0.05 were shown in bold. * indicates significance after Bonferroni correction
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Nutrition & Metabolism

ISSN: 1743-7075

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