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Table 3 Odds ratio (95% confidence intervals) of GDM associated with different levels of RBP4 in the first trimester and second trimester

From: Plasma retinol-binding protein 4 in the first and second trimester and risk of gestational diabetes mellitus in Chinese women: a nested case-control study

 Quartiles of RBP4P for trendPer 1 log increment
Q1Q2Q3Q4
First trimester
 Median (range)5.8 (4.2–8.2)12.9 (11.4–14.0)20.6 (17.7–22.7)42.1 (32.5–61.6)  
 Cases (%)31 (45.6)28 (41.8)34 (50.0)42 (62.7)  
 Model 1a1.001.07 (0.44–2.64)2.06 (0.76–5.58)3.63 (1.30–10.12)0.0043.60 (1.29–10.03)
 Model 2b1.001.06 (0.41–2.71)2.58 (0.86–7.75)3.72 (1.27–10.87)0.0053.14 (1.09–9.06)
 Model 3c1.001.06 (0.41–2.74)2.60 (0.86–7.86)3.71 (1.27–10.84)0.0053.12 (1.08–9.04)
Second trimester
 Median (range)5.9 (4.6–8.9)13.3 (12.0–14.9)20.1 (17.8–23.7)40.2 (30.1–54.9)  
 Cases (%)32 (47.8)27 (39.7)35 (52.2)41 (60.3)  
 Model 1a1.000.89 (0.36–2.17)2.30 (0.78–6.79)3.26 (1.09–9.72)0.0183.62 (1.17–11.25)
 Model 2b1.000.88 (0.34–2.25)2.88 (0.88–9.42)3.25 (1.02–10.34)0.0263.34 (1.03–10.85)
 Model 3c1.000.89 (0.35–2.30)2.95 (0.90–9.69)3.30 (1.03–10.52)0.0283.38 (1.03–11.08)
  1. Abbreviations: GDM Gestational diabetes mellitus, RBP4 Retinol-binding protein 4
  2. a Model 1: adjusted for maternal age, education, occupation, gestational weeks of RBP4 measurements in the first trimester, pre-pregnancy BMI, GWG before OGTT, SBP, DBP
  3. b Model 2: Model 1 additional adjusted total cholesterol, triglyceride, HDL, LDL, GFR, ALT, AST
  4. c Model 3: Model 2 additional adjusted daily intake of calories and weekly physical activity time