Fig. 3

Effect of resveratrol on the regulation of autophagy in osteoblasts and osteoclasts. a and b The osteoblasts were isolated from the rat lumbar vertebrae (L1-L5) in each group, and the protein levels of p62, LC3I/LC3II, atg5, atg7, and atg12 were measured by Western blotting; c and d The osteoclasts were isolated from the rat lumbar vertebrae (L1-L5) in each group, and the protein levels of p62, LC3I/LC3II, atg5, atg7, and atg12 were measured by Western blotting. LC3, protein microtubule-associated protein 1 light chain-3; Atg, autophagy related gene. The data were shown as the mean ± SD (n = 3). Compared to the Sham group, *p < 0.05, **p < 0.01, ***p < 0.001; Compared to the OVX group, # p < 0.05, ## p < 0.01, ### p < 0.001