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Table 3 Association of vitamin D status with lipid profile and hs-CRP in the second trimestera

From: Vitamin D status affects the relationship between lipid profile and high-sensitivity C-reactive protein

Variables β (95%CI) Vitamin D Status
25(OH)D ≥ 50 nmol/L 25(OH)D<50 nmol/L
TC(mg/dL)
 Model 1b −0.212(− 0.304,-0.120)* −8.384(−11.965,-4.803)* Refd
 Model 2c − 0.248(− 0.344,-0.152)* −8.690(− 12.333,-5.046)* Ref
TG(mg/dL)   
 Model 1b −0.477(− 0.689,-0.265)* −13.630(−21.916,-5.344)* Ref
 Model 2c −0.468(− 0.687,-0.250)* −13.254(− 21.544,-4.963)* Ref
HDL-C(mg/dL)
 Model 1b −0.018(− 0.050,0.014) −1.307(−2.554,-0.060)* Ref
 Model 2c − 0.045(− 0..078,-0.011)* −1.910(−3.176,-0.644)* Ref
LDL-C(mg/dL)
 Model 1b −0.171(− 0.234,-0.107)* −5.360(−7.831,-2.888)* Ref
 Model 2c − 0.176(− 0.242,-0.109)* −4.933(− 7.458,-2.409)* Ref
Hs-CRP(mg/L)
 Model 1b − 0.002(− 0.003,-0.001)* − 0.050(− 0.080,-0.019)* Ref
 Model 2c −0.002(− 0.002,-0.001)* −0.034(− 0.064,-0.004)* Ref
  1. a.25(OH)D 25-Hydroxyvitamin D; hs-CRP High-sensitivity C-reactive protein; TC Total cholesterol; TG Triglyceride; HDL-C High density lipoprotein-cholesterol; LDL-C Low density lipoprotein-cholesterol; Unit conversion factors: TC, HDL-C, LDL-C((mg/dL) × 0.0259 = mmol/L); TG((mg/dL) × 0.0113 = mmol/L);
  2. b.Model 1 unadjusted confounding factor;
  3. c.Model 2 controls confounding factors based on Model 1, including adjusted for sociodemographic characteristics (maternal age, education, income, season), perinatal health status(pre-pregnancy BMI, systolic blood pressure and diastolic blood pressure), lifestyle(sedentary time, physical activities, paternal alcohol and smoking consumption, fish oil supplement, multivitamin supplement, milk intake, soy product intake and dessert intake), hs-CRP or lipid profile
  4. d. “Refd” indicates 25(OH)D<50 nmol/L as a reference group
  5. * Indicates P < 0.05