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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: Circulating metabolites from the choline pathway and acute coronary syndromes in a Chinese case-control study

Fig. 1

Spearman correlations of the choline pathway metabolites in all participants. Red represents a positive correlation, blue represents a negative correlation, and the number in the matrix is the coefficients of spearman correlation

The inverse normal transformation was applied to the raw values of metabolites. To build the score, we applied a weighted sum of concentrations of 4 metabolites in the choline pathway (betaine, choline, TMA and TMAO). The ratio of betaine/choline was calculated by dividing the raw values and then applying the inverse normal transformations.

TMA, trimethylamine; TMAO, trimethylamine N-oxide

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