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Table 2 Baseline and 8-week body composition and fat distribution outcomes by diet group

From: Effects of weight loss during a very low carbohydrate diet on specific adipose tissue depots and insulin sensitivity in older adults with obesity: a randomized clinical trial

  LFD VLCD P
for diet
P
for diet adjusted for change in total fat
Week 0 Week 8 Week 0 Week 8   
Weight (kg) 96.8 ± 30.9 95.9 ± 28.4 93.7 ± 15.1 87.8 ± 12.5*** < 0.001 0.41
Total fat (kg) 40.3 ± 7.5 39.5 ± 7.5* 42.4 ± 9.6 38.3 ± 10.9*** < 0.001
VAT (kg) 1.8 ± 0.8 1.7 ± 0.8 2.2 ± 1.0 1.7 ± 0.7*** < 0.01 .99
VAT (cm3) 2077.6 ± 1038 2145.4 ± 1056.8 2613.6 ± 943.5 2249.2 ± 778.2** 0.01 0.58
SAAT (cm3) 5496.8 ± 2049 5116.8 ± 2117.3 5481.1 ± 2499.3 4340.9 ± 1626** 0.05 0.15
Thigh SAT (cm3) 349.6 ± 225.5 346.2 ± 216.1 317.2 ± 199.7 289.6 ± 186.4** 0.08 0.91
Thigh PMAT (cm3) 36.2 ± 16.2 36.4 ± 18.3 33.8 ± 11.3 30.9 ± 13.8 0.13 0.46
Thigh IMAT (cm3) 15.1 ± 6.6 15.7 ± 8.7 20.9 ± 13.4 15.8 ± 9.9*** < 0.01 0.02
Thigh SM (cm3) 345.9 ± 78.8 339.4 ± 76.3 366.5 ± 95.2 354.3 ± 84.9 0.67 0.02
Total lean (kg) 47.3 ± 7.2 48.0 ± 6.9 50.3 ± 1.2 48.8 ± 1.2** 0.01 0.07
  1. Data presented as mean ± SD
  2. *p < 0.05, **p < 0.01, ***p < 0.001 for paired t-test; P for effect of diet, results from ANCOVA (8-week outcome adjusted for baseline); P for the effect of diet, results from ANCOVA (8-week outcome adjusted for baseline and change in fat mass); VAT visceral adipose tissue, SAAT subcutaneous abdominal adipose tissue, IMAT intermuscular adipose tissue, PMAT perimuscular adipose tissue, SAT subcutaneous adipose tissue, SM skeletal muscle
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