Table 2 Summary of Technical Depth of Orbitrap-, QTOF-, and Triple-TOF-based Studies. A protein only needs to be identified in one sample to contribute to the total number of unique proteins (indicated as “total” below), thus the total is typically larger in studies with greater sample numbers. An iTRAQ or TMT set is a pool of samples that are run on the LC-MS/MS concurrently. Because the samples in a set are all analyzed simultaneously, a set's contribution to the total number of unique proteins is similar to that of a single sample

[30]

2018

Orbitrap

mouse embryo heads

group 1: 313 total

group 2: 372 total

2 groups

[31]

2018

Triple-TOF

gerbil plasma

109 total

30

[32, 185, 187]

2015

Orbitrap

human plasma

4,705 total

589/set

72 iTRAQ sets

[42]

2018

QTOF

rat thalami

1,440 total

6 x 3 tech. reps.

[51]

2017

QTOF

duck livers

1,749 total

3 iTRAQ sets

[52]

2019

QTOF

fetal duck livers

3,801 total

1 iTRAQ set

[91]

2019

Triple-TOF

rat hippocampi

4,807 total

2 iTRAQ sets

[120]

2015

Orbitrap

human follicular fluid

227 total

1 TMT set

[121]

2014

QTOF

mouse intestine

2,039 total

10

[156]

2019

Orbitrap

pig plasma

534 total

45

[157]

2018

Orbitrap

mouse liver fraction

4,058 total

9

[158]

2014

QTOF

zebrafish

2,956 total

19

[183]

2016

Orbitrap

mouse lung

1,160 total,

240 common to all

34

[184]

2018

Orbitrap

mouse brain

5,062 total

1 TMT set

[188]

2016

Orbitrap

human serum

1,841 total

1 iTRAQ set

[186]

2019

Orbitrap

mouse brain tissues

group 1: 5,847 total

group 2: 6,047 total

2 groups of 6

[206]

2013

QTOF

rabbit aortae

100 total

24 x 3 tech. reps.