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Table 4 Correlation between Klotho protein and FGF23 protein, TGF-β protein, caspase-3 protein, c-fos and BDNF gene expression (n = 3 and technical replication is 3)

From: High-protein and low-calorie diets improved the anti-aging Klotho protein in the rats’ brain: the toxic role of high-fat diet

Correlation measured factors (Pearson coefficients correlation)
FGF23 TGF-β Caspase-3 c-fos gene expression BDNF gene expression
Klotho
 Hippocampus
  r = 0.81 r = 0.65 r = 0.83 r = 0.81 r = 0.64
  P = 0.000 P = 0.003 P = 0.001 P = 0.000 P = 0.000
 Prefrontal cortex
  r = 0.63 r = 0.64 r = 0.80 r = 0.80 r = 0.66
  P = 0.000 P = 0.001 P = 0.001 P = 0.000 P = 0.000
  1. P value less than 0.05 considered significant