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Table 4 ORs and 95% Cls for quartiles of dietary nutrients intake with cervical intraepithelial neoplasia grade1 risk among 2304 women in the studya

From: Dietary nutrient intake related to higher grade cervical intraepithelial neoplasia risk: a Chinese population-based study

  Quartiles of dietary nutrientsb
Q1 Q2 Q3 Q4 P-trendc
Folate      
 Median intake (μg/day) 297 381 488 764  
 No. of cases 132 147 139 146  
 Model 1 0.91 (0.69–1.20) 1.01 (0.77–1.32) 0.91 (0.69–1.19) 1.00 (reference) < 0.001
 Model 2 0.95 (0.72–1.26) 1.04 (0.79–1.37) 0.92 (0.70–1.21) 1.00 (reference) 0.012
 Model 3 0.96 (0.72–1.27) 1.04 (0.79–1.37) 0.91 (0.69–1.21) 1.00 (reference) 0.020
Vitamin B1      
 Median intake (mg/day) 1.1 1.4 1.9 2.7  
 No. of cases 134 157 132 141  
 Model 1 0.91 (0.68–1.22) 1.25 (0.95–1.65) 0.89 (0.68–1.15) 1.00 (reference) < 0.001
 Model 2 0.98 (0.73–1.31) 1.31 (0.99–1.74) 0.89 (0.68–1.17) 1.00 (reference) 0.011
 Model 3 0.99 (0.74–1.34) 1.33 (1.00–1.77) 0.91 (0.69–1.19) 1.00 (reference) 0.017
Vitamin B2      
 Median intake (mg/day) 1.1 1.4 1.8 2.7  
 No. of cases 123 148 157 136  
 Model 1 0.85 (0.64–1.12) 1.13 (0.85–1.48) 1.08 (0.82–1.42) 1.00 (reference) < 0.001
 Model 2 0.88 (0.66–1.17) 1.16 (0.88–1.54) 1.09 (0.83–1.44) 1.00 (reference) 0.011
 Model 3 0.87 (0.66–1.17) 1.15 (0.86–1.52) 1.10 (0.83–1.45) 1.00 (reference) 0.020
Vitamin B6      
 Median intake (mg/day) 1.7 2.1 2.6 3.9  
 No. of cases 144 146 131 143  
 Model 1 1.04 (0.79–1.36) 0.99 (0.76–1.30) 0.90 (0.69–1.19) 1.00 (reference) < 0.001
 Model 2 1.08 (0.82–1.43) 1.00 (0.76–1.32) 0.90 (0.68–1.19) 1.00 (reference) < 0.001
 Model 3 1.09 (0.83–1.44) 0.99 (0.75–1.31) 0.91 (0.69–1.21) 1.00 (reference) 0.019
Vitamin C      
 Median intake (mg/day) 46.0 62.8 86.9 138.9  
 No. of cases 124 149 145 146  
 Model 1 0.85 (0.65–1.13) 1.05 (0.81–1.38) 1.01 (0.77–1.33) 1.00 (reference) < 0.001
 Model 2 0.87 (0.65–1.16) 1.09 (0.83–1.44) 1.04 (0.79–1.36) 1.00 (reference) 0.012
 Model 3 0.86 (0.65–1.15) 1.09 (0.83–1.44) 1.04 (0.79–1.37) 1.00 (reference) 0.021
Vitamin E      
 Median intake (mg/day) 4.4 8.8 10.8 21.7  
 No. of cases 131 135 151 147  
 Model 1 0.83 (0.63–1.09) 0.86 (0.65–1.13) 1.08 (0.83–1.42) 1.00 (reference) < 0.001
 Model 2 0.84 (0.63–1.11) 0.88 (0.67–1.16) 1.09 (0.83–1.44) 1.00 (reference) 0.013
 Model 3 0.85 (0.64–1.12) 0.87 (0.66–1.16) 1.10 (0.83–1.45) 1.00 (reference) 0.023
Vitamin K      
 Median intake (μg/day) 133.0 194.0 285.0 534.0  
 No. of cases 125 159 139 141  
 Model 1 0.94 (0.71–1.23) 1.23 (0.93–1.62) 1.00 (0.77–1.31) 1.00 (reference) < 0.001
 Model 2 0.96 (0.73–1.27) 1.24 (0.94–1.64) 1.01 (0.77–1.33) 1.00 (reference) 0.010
 Model 3 0.98 (0.74–1.29) 1.24 (0.94–1.65) 1.03 (0.79–1.36) 1.00 (reference) 0.017
Niacin      
 Median intake (mg/day) 17.7 21.6 27.9 42.8  
 No. of cases 147 140 135 142  
 Model 1 1.11 (0.84–1.46) 0.96 (0.73–1.27) 0.96 (0.73–1.26) 1.00 (reference) < 0.001
 Model 2 1.14 (0.86–1.51) 0.97 (0.74–1.28) 0.93 (0.71–1.23) 1.00 (reference) 0.012
 Model 3 1.15 (0.87–1.53) 0.96 (0.73–1.26) 0.94 (0.72–1.25) 1.00 (reference) 0.020
Dietary fiber      
 Median intake (g/day) 27.4 34.5 43.7 63.2  
 No. of cases 138 148 136 142  
 Model 1 0.99 (0.75–1.30) 1.07 (0.82–1.41) 0.92 (0.70–1.21) 1.00 (reference) < 0.001
 Model 2 1.05 (0.79–1.39) 1.12 (0.85–1.47) 0.93 (0.71–1.23) 1.00 (reference) 0.010
 Model 3 1.05 (0.79–1.39) 1.12 (0.85–1.48) 0.95 (0.72–1.25) 1.00 (reference) 0.018
  1. CIN1, cervical intraepithelial neoplasia grade 1; CI, confidence interval
  2. aValues are n or ORs (95% CIs) obtained from logistic regression analysis, based on the highest intake group as the reference, unless otherwise indicated
  3. bModel 1: odds ratios unadjusted; Model 2: odds ratios adjusted for age, education years, annual family salary, smoker, age at menarche, menopause status, IUD use, years of IUD use, Sexual activity in menstrual period, had gynecologic surgery, had vaginitis; Model 3: additionally odds ratios adjusted for high-risk HPV, SCJ visibility, vaginal pH
  4. cP values for differences between groups were obtained from the Bonferroni correction test for categoric variables
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Nutrition & Metabolism

ISSN: 1743-7075

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