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Table 4 Between-subject differences, optimal v. no response, on and before ketogenic diet

From: Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot study

During KD

responders / non-responders

Compound family

Compound

 

Ketone Bodies

β-hydroxybutyrate

3.24**

acetoacetate

3.88**

1,2-propanediol

4.74*

Monohydroxy Fatty Acids

γ-hydroxybutyrate

2.06**

3-hydroxyoctanoate

2.61**

Medium Chain Fatty Acid

hexanoic acid

2.79**

Triglyceride Metabolism

glycerol

1.34*

Glycolysis

glycerate

0.62*

glucose

0.88**

Hexoses

sorbose

0.28**

fructose

0.75**

Baseline

Acyl Carnitines

acetylcarnitine

0.72*

 Corticosteroids

cortisol

1.36*

 Hexoses

mannose

0.72**

 Tetroses

erythrulose

0.34*

  1. Ratios are fold difference between patients with an optimal vs. no clinical response. Only compounds with p < 0.10 are listed. *0.05 < p < 0.10, **p < 0.05
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Nutrition & Metabolism

ISSN: 1743-7075

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