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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: Hawthorn fruit extract reduced trimethylamine-N-oxide (TMAO)-exacerbated atherogenesis in mice via anti-inflammation and anti-oxidation

Fig. 2

Plasma levels of TMAO, inflammatory cytokines, and oxidative stress-related parameters in ApoE−/− mice. a Plasma level of TMAO. The inflammatory cytokines include b tumor necrosis factor α (TNF-α), c interleukin (IL)-1β, d IL-6, e monocyte chemoattractant protein 1 (MCP-1), and f IL-10. Plasma levels of g total antioxidant capacity (T-AOC), h superoxide dismutase (SOD) activity, i glutathione peroxidase (GSH-Px) activity, and j malondialdehyde (MDA) in ApoE−/− mice. Data are expressed as mean with SD, n = 8. a,b,cmeans with different superscript letters differ significantly at p < 0.05 by one-way ANOVA. p for dose effect was analyzed using ordinary linear regression across WD + TMAO, WD + TMAO + L-HFE, and WD + TMAO + H-HFE groups

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