|
Index
|
ND group
|
NDS group
|
HFD group
|
HFDS group
|
|---|
|
Body weight (g)
|
461.67 ± 23.89
|
462.67 ± 38.99
|
570.83 ± 23.02**
|
500.50 ± 23.72∆∆
|
|
Liver weight (g)
|
14.81 ± 1.05
|
14.05 ± 1.98
|
21.01 ± 1.41**
|
19.24 ± 0.93∆∆
|
|
Liver index (%)
|
3.21 ± 0.19
|
3.03 ± 0.32
|
3.68 ± 0.23**
|
3.85 ± 0.12∆∆
|
|
Lee’s index
|
3.00 ± 0.08
|
3.05 ± 0.06
|
3.19 ± 0.05**
|
3.10 ± 0.10
|
|
TC (mmol/L)
|
1.43 ± 0.40
|
1.38 ± 0.30
|
2.59 ± 0.16**
|
2.19 ± 0.29∆∆
|
|
TG (mmol/L)
|
0.64 ± 0.19
|
0.67 ± 0.39
|
1.47 ± 0.26**
|
1.09 ± 0.16∆∆
|
|
ALT (U/L)
|
41.83 ± 6.76
|
44.87 ± 9.26
|
106.48 ± 18.35**
|
87.00 ± 8.10∆
|
|
AST (U/L)
|
145.23 ± 17.95
|
182.08 ± 40.23
|
429.67 ± 56.46**
|
364.18 ± 40.04∆∆
|
|
FBG(mmol/L)
|
8.01 ± 1.21
|
8.92 ± 2.07
|
13.36 ± 1.02**
|
12.22 ± 1.41
|
|
FINS (mIU/L)
|
22.27 ± 2.17
|
23.58 ± 1.05
|
31.80 ± 4.27**
|
29.31 ± 1.79
|
|
HOMA-IR
|
9.23 ± 1.44
|
11.25 ± 1.98
|
15.88 ± 2.12**
|
13.67 ± 0.53∆
|
|
FINS (mIU/L)
|
10.55 ± 0.67
|
10.73 ± 1.62
|
18.82 ± 1.20**
|
16.03 ± 5.54∆
|
|
HOMA-IR
|
3.78 ± 0.80
|
4.37 ± 1.75
|
11.17 ± 1.12**
|
8.80 ± 2.07∆
|
- Liver index = (liver weight/body weight) × 100%; Lee’s index = (weight × 1000)^(1/3)/length (cm); Total cholesterol (TC); Triglyceride TG; Alanine aminotransferase ALT; Aspartate aminotransferase AST; Fasting blood glucose FBG; Insulin level FINS; Insulin resistance level HOMA-IR = (FINS*FBG)/22.5. *p ≤ 0.05 and **p ≤ 0.01 represented statistically significance between HFD group and ND group; ∆p ≤ 0.05 and ∆∆p ≤ 0.01 represented statistically significance between HFDS group and HFD group. n = 6
