Fig. 1
From: Asiatic acid alleviates Ang-II induced cardiac hypertrophy and fibrosis via miR-126/PIK3R2 signaling
Asiatic Acid (AA) treatment inhibited AngII-induced cardiomyocytes growth and cardiac fibroblasts collagen expression in vitro. H9c2 and cardiac fibroblasts (CF) cells were exposed to AngII 10 µM with or without AA 160 µM for 24 h. Cell surface area was determined (a), mRNA level of ANP (b) and BNP (c) were quantified using real-time PCR. c α-SMA, Col1a1 and Col3a1 mRNA levels in AngII-induced and AA-treated CFs. Data are presented as mean ± SD, *P < 0.05, **P < 0.01