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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis in mice fed with high AGEs-fat diet

Fig. 5

Apoptosis in the colon. a and b Apoptotic epithelial cells in the colon crypts are shown, c the numbers of TUNEL-positive cells in the colon (at least 5 parts were evaluated for each sample). RNA levels of d Bcl2, e Bax, f P53, g ZO-1. HE: herbal extract; ND: normal diet; HFD: high AGEs-fat diet; HD: high dose; DSS: 2.5% dextran sulphate sodium; Bax: BCL2 Associated X, Apoptosis Regulator; Bcl2: BCL2 Apoptosis Regulator; P53: Tumor Protein P53; TUNEL: terminal deoxynucleotidyl transferase–mediated dUTP end labeling; ZO-1: zonula occludense-1. Data as mean with 95% CI, n = 6 per group. * and ** respectively represents p < 0.05 and p < 0.01 (significant difference between the groups)

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Nutrition & Metabolism

ISSN: 1743-7075

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