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Table 3 Risk of CVD events according to dietary intakes of saturated fats

From: The association between dietary fats and the incidence risk of cardiovascular outcomes: Tehran Lipid and Glucose Study

Saturated fats

Tertile 1

Tertile 2

Tertile 3

P for trend

Total saturated fats

 

Median intake (% of energy)

7.74

10.17

13.12

 

Range (% of energy)

2.30–9.04

9.05–11.38

11.38–196.91

 

CVD event (n)

93

62

43

 

HR (95% CI) Crude Model

1.00

0.74 (0.53–1.03)

0.45 (0.30–0.66)

 < 0.001

HR (95% CI) Model 1

1.00

0.89 (0.64–1.24)

0.68 (0.46–1.01)

0.061

HR (95% CI) Model 2

1.00

0.92 (0.63–1.34)

0.75 (0.45–1.23)

0.263

Lauric acid

 

Median intake (% of energy)

0.19

0.31

0.47

 

Range (% of energy)

0.02–0.25

0.25–0.37

0.37–4.53

 

CVD event (n)

87

70

41

 

HR (95% CI) Crude Model

1.00

0.94 (0.68–1.32)

0.54 (0.36–0.80)

 < 0.001

HR (95% CI) Model 1

1.00

1.27 (0.90–1.78)

0.75 (0.51–1.11)

0.228

HR (95% CI) Model 2

1.00

1.31 (0.93–1.84)

0.79 (0.52–1.18)

0.377

Myristic acid

 

Median intake (% of energy)

0.52

0.83

1.19

 

Range (% of energy)

0.06–0.68

0.68–0.97

0.97–4.81

 

CVD event (n)

85

71

42

 

HR (95% CI) Crude Model

1.00

0.85 (0.61–1.20)

0.65 (0.45–0.94)

0.007

HR (95% CI) Model 1

1.00

1.09 (0.77–1.54)

0.85 (0.59–1.23)

0.452

HR (95% CI) Model 2

1.00

1.17 (0.83–1.67)

0.94 (0.63–1.40)

0.874

Palmitic acid

 

Median intake (% of energy)

3.73

4.74

6.03

 

Range (% of energy)

1.87–4.27

4.27–5.28

5.28–14.42

 

CVD event (n)

77

68

53

 

HR (95% CI) Crude Model

1.00

0.60 (0.42–0.87)

0.77 (0.55–1.09)

0.113

HR (95% CI) Model 1

1.00

0.81 (0.56–1.17)

0.96 (0.68–1.36)

0.786

HR (95% CI) Model 2

1.00

0.85 (0.57–1.26)

1.05 (0.71–1.54)

0.800

Stearic acid

 

Median intake (% of energy)

1.51

1.96

2.49

 

Range (% of energy)

0.67–1.74

1.74–2.19

2.19–6.69

 

CVD event (n)

90

65

43

 

HR (95% CI) Crude Model

1.00

0.61 (0.44–0.85)

0.45 (0.31–0.65)

 < 0.001

HR (95% CI) Model 1

1.00

0.80 (0.57–1.12)

0.69 (0.48–1.01)

0.052

HR (95% CI) Model 2

1.00

0.79 (0.54–1.16)

0.70 (0.42–1.16)

0.150

  1. Data are hazard ratio (95% CI); proportional hazard Cox regression was used. HR, Hazard Ratio; CI, Confidence Interval; CVD, Cardio-vascular Disease
  2. Model 1 was adjusted for sex, waist circumference, body mass index, CVD score, hypertension and physical activity. Model 2 was additionally adjusted for total energy intake (kcal/d), total fat (g/d), total fiber (g/d), cholesterol (mg/d), tea and coffee intake (ml/d)