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Table 2 Adjusted hazard ratios (95% CIs) of diabetes by the menopausal status and age at natural menopause

From: Menopausal status, age at natural menopause and risk of diabetes in China: a 10-year prospective study of 300,000 women

 

Total/cases

Model 1

Model 2

Model 3

Model 4

Menopausal status

 Pre-

125,494/3,055

1.00

1.00

1.00

1.00

 Peri-

14,036/664

1.18 (1.07–1.30) *

1.18 (1.07–1.30) *

1.18 (1.07–1.30) *

1.17 (1.06–1.29) *

 Post-

141,789/7,740

1.11 (1.02–1.20) *

1.15 (1.06–1.25) *

1.16 (1.07–1.25) *

1.15 (1.06–1.25) *

Age at menopause, year

 < 40

5,890/311

1.15 (1.01–1.29) *

1.15 (1.01–1.29) *

1.15 (1.01–1.31) *

1.14 (1.01–1.30) *

 40–44

16,523/819

1.00 (0.93–1.08)

1.01 (0.93–1.09)

1.01 (0.93–1.09)

1.01 (0.93–1.09)

 45–49

58,998/3,012

1.00

1.00

1.00

1.00

 50–53

49,346/2,882

1.14 (1.08–1.20) *

1.10 (1.05–1.16) *

1.11 (1.05–1.17) *

1.10 (1.04–1.16) *

≧ 54

11,032/716

1.18 (1.09–1.28) *

1.11 (1.02–1.20) *

1.10 (1.00–1.19) *

1.10 (1.01–1.20) *

  1. Model 1 adjusted for education, household income; model 2 adjusted for model 1 plus health behaviors of smoking, alcohol drinking, physical activity (Metabolic Equivalents of Task, h/d), and anthropometric measurements including body mass index, waist circumference; model 3 adjusted for model 2 plus health status of hypertension, and family history of diabetes; model 4 adjusted for model 3 plus reproductive factors of age at menarche, number of live births, age at first birth, breastfeeding duration per child, and oral contraceptive use
  2. All models were stratified by age and study area
  3. *Significant results