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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: Magnesium isoglycyrrhizinate attenuates acute alcohol-induced hepatic steatosis in a zebrafish model by regulating lipid metabolism and ER stress

Fig. 1

MgIG ameliorate acute alcohol induced-hepatic steatosis in zebrafish Larvae. a 5 dpf larvae were treated as indicated for 32 h and stained with whole-mount oil red O. The typical pictures of each group were shown. Arrows point to the liver. b Hepatic steatosis was defined as three or more lipid droplets deposition in liver. Bar chart indicates the percentage of larvae with steatosis (n = 97–223 each group; *P < 0.05 by one-way ANOVA). c H&E staining of paraffin sections through the livers of larvae treated as indicated. Clear cytoplasmic lipid droplets were seen in livers from larvae fed with alcohol. MgIG treatment decreased lipid droplets and ameliorated hepatic steatosis in alcohol-treated zebrafish larvae. d TC levels in the livers of zerafish larvae in each group. e TG levels in the livers of zerafish larvae in each group. (n = 50–60 each group; *P < 0.05, **P < 0.01, ***P < 0.001, by one-way ANOVA)

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Nutrition & Metabolism

ISSN: 1743-7075

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