Fig. 3

Association of VAT^ with total fracture risk using restricted cubic splines. HRs are indicated by solid lines and 95% CIs by shaded areas. The reference point was the median of VAT^ in men (1.67 kg) and women (0.69 kg), separately, with knots placed at the 5th, 25th, 50th, 75th, and 95th centiles of each VAT^ distribution. All models were adjusted for age, household income, lean mass, standing height, smoking status, alcohol consumption, physical activity, calcium supplement use, vitamin D supplement use, overall health rating, diabetes, cardiovascular disease, cancer, and for women, menopausal status and use of hormone replacement therapy. VAT^ predicted values of VAT (visceral adipose tissue) mass; HR hazard ratio; and CI confidence interval