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Table 1 Characteristics of the subjects enrolled in the study and results of laboratory tests: Controls, patients with small intestinal bacterial overgrowth and diarrhea predominant (SIBO-D), patients with small intestinal bacterial overgrowth and constipation predominant (SIBO-C); Mean ± SD

From: Antimicrobial treatment improves tryptophan metabolism and mood of patients with small intestinal bacterial overgrowth

Feature

Control

SIBO-D

SIBO-C

p

Age (years)

43.9 ± 5.3

47.4 ± 8.5

48.3 ± 12.6

Ns

Gender – M/F

19/21

17/23

15/25

Ns

BMI (kg/m2)

23.7 ± 1.8

22.9 ± 1.1

25.2 ± 2.4

Ns

GFR (ml/min)

101.3 ± 9.6

102.6 12.8

98.1 ± 10.6

Ns

ALT (U/L)

14.2 ± 2.6

19.4 ± 8.7

19.6 ± 12.5

Ns

AST (U/L)

12.9 ± 3.1

18.2 ± 5.8

21.7 ± 8.2

Ns

CRP (mg/L)

1.24 ± 0.32

7.16 ± 1.32

2.92 ± 1.46

 < 0.01a

FC (µg/g)

21.8 ± 7.32

48.8 ± 18.3

32.6 ± 16.4

 < 0.01a

LHBT (ppm)

10.3 ± 3.62

68.1 ± 15.9

57.4 ± 13.4

 < 0.001a

TRP (mg/24 h)

1296 ± 198

1139 ± 162

1306 ± 301

Ns

  1. M Male, F Female, BMI Body mass index, GFR Glomerular filtrating ratio, ALT Alanine aminotransferase, AST Aspartate aminotransferase, CRP C-reactive protein, FC Fecal calprotectin, LHBT Lactulose hydrogen breath test, TRP L-tryptophan, Ns – p > 0.05, differences between groups: a – group C vs group SIBO-D