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Table 4 Correlation between 11 lipids selected and therapeutic effect of TCM

From: High-coverage targeted lipidomics could reveal lipid alterations and evaluate therapeutic efficacy of membranous nephropathy

Name

Model 1

Model 2

Model 3

Model 4

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

TG52:0-FA20:0

0.602 (0.385, 0.941)

0.026

0.575 (0.360, 0.920)

0.021

0.577 (0.359, 0.926)

0.023

0.636 (0.384, 1.053)

0.078

TG54:2-FA20:0

0.594 (0.382, 0.922)

0.020

0.573 (0.362, 0.906)

0.017

0.572 (0.360, 0.910)

0.018

0.629 (0.384, 1.028)

0.064

TG55:3-FA18:2

0.565 (0.353, 0.904)

0.017

0.573 (0.352, 0.933)

0.025

0.581 (0.350, 0.963)

0.035

0.624 (0.354, 1.099)

0.103

TG55:4-FA18:2

0.557 (0.349, 0.888)

0.014

0.565 (0.349, 0.914)

0.020

0.568 (0.346, 0.931)

0.025

0.619 (0.362, 1.061)

0.081

TG55:5-FA18:2

0.581 (0.369, 0.916)

0.019

0.575 (0.358, 0.922)

0.022

0.578 (0.357, 0.935)

0.026

0.624 (0.376, 1.034)

0.067

TG56:2-FA20:0

0.537 (0.339, 0.851)

0.008

0.533 (0.332, 0.856)

0.009

0.532 (0.330, 0.860)

0.010

0.576 (0.347, 0.958)

0.033

TG56:2-FA20:1

0.517 (0.322, 0.832)

0.007

0.529 (0.327, 0.855)

0.009

0.528 (0.322, 0.865)

0.011

0.554 (0.316, 0.971)

0.039

TG56:3-FA20:0

0.540 (0.337, 0.865)

0.010

0.541 (0.332, 0.881)

0.014

0.536 (0.328, 0.877)

0.013

0.586 (0.350, 0.981)

0.042

TG56:4-FA18:2

0.522 (0.324, 0.842)

0.008

0.536 (0.328, 0.876)

0.013

0.529 (0.319, 0.878)

0.014

0.573 (0.325, 1.010)

0.054

TG56:5-FA20:2

0.565 (0.353, 0.904)

0.007

0.520 (0.318, 0.849)

0.009

0.515 (0.312, 0.850)

0.009

0.540 (0.306, 0.953)

0.033

TG56:9-FA20:5

0.557 (0.349, 0.888)

0.131

0.612 (0.368, 1.016)

0.057

0.617 (0.367, 1.036)

0.068

0.688 (0.356, 1.330)

0.266

  1. Bold means p value ≤ 0.05
  2. Model 1: Adjusted for sex, age, hypertension, and diabetes
  3. Model 2: Adjusted for Model 1, albumin, creatinine, uric acid, 24hpro
  4. Model 3: Adjusted for Model 2, Hb and urea nitrogen
  5. Model 4: Adjusted for Model 3, HDL, LDL, TG, CHOL