Table 4 Association of ischemic and hemorrhagic stroke with alcohol intake and rs12514417 genotypes
From: ALDH7A1 rs12514417 polymorphism may increase ischemic stroke risk in alcohol-exposed individuals
| Â | Ischemic stroke | Hemorrhagic stroke | ||
|---|---|---|---|---|
OR | (95% CI) | OR | (95% CI) | |
TT, alcohol intake | 0.91 | (0.68–1.22) | 1.59 | (0.75–3.38) |
TG + GG, no alcohol intake | 1.08 | (0.92–1.27) | 0.72 | (0.39–1.34) |
TG + GG, alcohol intake | 1.64 | (1.15–2.33) | 1.24 | (0.37–4.17) |
Sex (ref: Female) | Â | Â | Â | Â |
Male | 1.03 | (0.87–1.22) | 1.19 | (0.67–2.11) |
Age | 1.07 | (1.06–1.08) | 1 | (0.98–1.03) |
Education (ref: Elementary School) | Â | Â | Â | Â |
Junior & Senior High School | 1.08 | (0.86–1.36) | 0.85 | (0.34–2.10) |
University & above | 0.89 | (0.70–1.14) | 0.64 | (0.25–1.66) |
Smoking (ref: N0) | Â | Â | Â | Â |
Yes | 0.93 | (0.77–1.13) | 1.14 | (0.62–2.11) |
Physical activity (ref: No) | Â | Â | Â | Â |
Yes | 1.05 | (0.91–1.22) | 0.83 | (0.50–1.38) |
BMI | 1 | (0.98–1.02) | 0.98 | (0.91–1.05) |
Diabetes (ref: No) | Â | Â | Â | Â |
Yes | 1.47 | (1.25–1.74) | 1.47 | (0.77–2.79) |
Hypertension (ref: No) | Â | Â | Â | Â |
Yes | 2.33 | (1.98–2.74) | 1.37 | (0.75–2.49) |
Hyperlipidemia (ref: No) | Â | Â | Â | Â |
Yes | 1.64 | (1.39–1.93) | 1.42 | (0.80–2.54) |