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Table 2 Association of 17 candidate SNP alleles with the increased weight growth trajectory in the Taiwan Puberty Longitudinal Study

From: Association between genetic risk score and tri-ponderal mass index growth trajectories among different dietary consumption adolescents in a prospective Taiwanese cohort

SNP

Nearest gene

Chr.

Allele

Increased weight vs. Stable weight

 

Effect

Other

ORa

95% CI

p value

rs7206790

FTO

16

C

G

2.13*

1.08, 4.21

0.03

rs2531995

ADCY9

16

T

C

1.47

0.91, 2.37

0.11

rs4715210

TFAP2B

6

C

T

1.66

0.85, 3.28

0.14

rs6548238

TMEM18

2

C

T

1.95

0.78, 4.84

0.15

rs12463617

TMEM18

2

C

A

1.92

0.77, 4.80

0.16

rs1555543

PTBP2

1

C

A

1.73

0.77, 3.91

0.18

rs8053360

IRX3

16

C

T

1.98

0.58, 6.77

0.28

rs9939609

FTO

16

T

A

1.32

0.71, 2.46

0.37

rs7498665

SH2B1

16

A

G

1.15

0.62, 2.15

0.66

rs4788102

SH2B1

16

G

A

1.15

0.61, 2.15

0.67

rs12597579

GP2

16

C

T

1.09

0.68, 1.76

0.71

rs9356744

CDKAL1

6

T

C

1.07

0.71, 1.61

0.76

rs3817334

MTCH2

11

T

C

1.07

0.68, 1.67

0.80

rs574367

SEC16B

1

G

T

1.08

0.61,1.92

0.80

rs1421085

FTO

16

T

C

1.07

0.60, 1.90

0.82

rs6567160

MC4R

18

C

T

1.03

0.60, 1.75

0.92

rs16858082

GNPDA2

4

T

C

1.03

0.64, 1.65

0.92

  1. Chr. chromosome, CI confidence interval, OR odds ratio, SNP single-nucleotide polymorphism, TMI Tri-ponderal mass index
  2. aMultinomial logistic regression with the additive model for each SNP, adjusted for gender, age, baseline TMI, parental education level, family income, Tanner stage, and exercise habit
  3. *p-value < 0.05