Table 1 Demographic and clinicopathological characteristics
Demographic or clinicopathological characteristic | Primary cohort (N = 1373) | Internal validation cohort (N = 409) | P value |
|---|---|---|---|
No. of patients (%) | No. of patients (%) | Â | |
General information | Â | Â | Â |
Age, > 65 years | 421 (30.7) | 122 (29.8) | 0.795 |
Sex, male | 803 (58.5) | 247 (60.4) | 0.528 |
Smoking status, yes | 517 (37.7) | 159 (38.9) | 0.698 |
Alcohol consumption, yes | 251 (18.3) | 72 (17.6) | 0.811 |
Tea consumption, yes | 374 (27.2) | 127 (31.1) | 0.149 |
Comorbid disease(s) | Â | Â | 0.932 |
 0 | 877 (63.9) | 261 (63.8) |  |
 1 | 377 (27.5) | 109 (26.7) |  |
 2 | 95 (6.9) | 32 (7.8) |  |
 3 or more | 24 (1.7) | 7 (1.7) |  |
Family history of cancer, yes | 193 (14.1) | 58 (14.2) | 1 |
TNM stage | Â | Â | 0.378 |
 I | 99 (7.2) | 33 (8.1) |  |
 II | 344 (25.1) | 116 (28.4) |  |
 III | 441 (32.1) | 116 (28.4) |  |
 IV | 489 (35.6) | 144 (35.2) |  |
Radical resection, yes | 539 (39.3) | 163 (39.9) | 0.874 |
Nutrition related information | Â | Â | Â |
PGSGA Criteria (nutritional index) | Â | Â | 0.365 |
Well nourished (0–3) | 449 (32.7) | 149 (36.4) |  |
Moderately malnourished (4–8) | 537 (39.1) | 149 (36.4) |  |
Severely malnourished (> 9) | 387 (28.2) | 111 (27.1) |  |
Weight loss, yes | 685 (49.9) | 207 (50.6) | 0.842 |
Reduced intake, yes | 588 (42.8) | 163 (39.9) | 0.874 |
Activities and function declined, yes | 473 (34.5) | 143 (35.0) | 0.895 |
BMI, kg/m2 | Â | Â | 0.676 |
 < 18.5 | 153 (11.1) | 40 (9.8) |  |
 18.5–23.9 | 770 (56.1) | 235 (57.5) |  |
 24–27.9 | 367 (26.7) | 114 (27.9) |  |
 ≥ 28 | 83 (6.0) | 20 (4.9) |  |
Nutritional intervention, yes | 334 (24.3) | 99 (24.2) | 1 |
Serum total protein, < 60 g/L | 263 (19.2) | 71 (17.4) | 0.456 |
Serum albumin, < 35 g/L | 373 (27.2) | 92 (22.5) | 0.608 |