Table 1 Clinical characteristics in the first examination in 2013–2014 according to fat% change categories
Fat% change categories | P value | ||||
|---|---|---|---|---|---|
< – 8% | – 8% to < –2% | – 2% to < 2% | ≥ 2% | ||
Demographics | |||||
Men/women, n | 101/95 | 105/116 | 56/133 | 194/248 | < 0.001 |
Age, years | 60 (55, 63) | 60 (56, 64) | 61 (57, 64) | 60 (56, 63) | 0.339 |
BMI, kg/m2 | 23.2 (21.5, 24.7) | 24.4 (22.6, 26.6) | 24.2 (22.7, 26.1) | 23.2 (21.1, 25.0) | < 0.001 |
Social history | |||||
Above high school, n (%) | 119 (60.7) | 138 (62.4) | 113 (59.8) | 273 (61.8) | 0.946 |
Current smoker, n (%) | 50 (25.5) | 43 (19.5) | 25 (13.2) | 113 (25.6) | 0.003 |
Family history of CVD, n (%) | 62 (31.6) | 78 (35.3) | 72 (38.1) | 150 (33.9) | 0.590 |
Physical activity, n (%) | 0.661 | ||||
Low | 38 (19.4) | 43 (19.5) | 29 (15.3) | 84 (19.0) | |
Moderate | 85 (43.4) | 104 (47.1) | 87 (46.0) | 215 (48.6) | |
High | 73 (37.2) | 74 (33.5) | 73 (38.6) | 143 (32.4) | |
Comorbidities | |||||
Hypertension, n (%) | 104 (53.1) | 124 (56.1) | 104 (55.0) | 188 (42.5) | 0.001 |
Diabetes, n (%) | 38 (19.4) | 47 (21.3) | 42 (22.2) | 85 (19.2) | 0.808 |
Dyslipidemia, n (%) | 132 (67.3) | 168 (76.0) | 149 (78.8) | 301 (68.1) | 0.010 |
Medication | |||||
Antihypertensive drug, n (%) | 49 (25.0) | 64 (29.0) | 65 (34.4) | 117 (26.5) | 0.152 |
Antidiabetic drug, n (%) | 19 (9.7) | 17 (7.7) | 16 (8.5) | 37 (8.4) | 0.907 |
Lipid drug, n (%) | 20 (10.2) | 34 (15.4) | 28 (14.8%) | 54 (12.2) | 0.353 |
Metabolic profile changes between first and second examinations | |||||
SBP, mmHg | − 3 (− 12, 7) | 0 (− 10, 12) | − 1 (− 9, 11) | 3 (− 7, 12) | 0.001 |
DBP, mmHg | − 3 (− 9, 2) | − 2 (− 8, 4) | − 2 (− 8, 4) | − 1 (− 6, 5) | 0.017 |
FPG, mmol/L | 0.42 (0.09, 0.90) | 0.41 (0.11, 0.90) | 0.66 (0.26, 1.08) | 0.75 (0.37, 1.16) | < 0.001 |
2hPG, mmol/L | − 0.06 (− 1.30, 1.09) | 0.30 (− 0.97, 1.66) | 0.43 (− 0.89, 1.70) | 0.53 (− 0.79, 1.80) | 0.009 |
HbA1c, % | 0.10 (− 0.20, 0.30) | 0.10 (0.00, 0.30) | 0.10 (− 0.10, 0.40) | 0.10 (0.00, 0.30) | 0.031 |
FINS, mU/L | − 0.31 (− 2.50, 1.81) | 0.47 (− 1.58, 2.45) | 0.82 (− 1.31, 3.99) | 2.00 (0.08, 4.50) | < 0.001 |
HOMA-IR | 0.04 (− 0.54, 0.70) | 0.30 (− 0.29, 0.86) | 0.45 (− 0.08, 1.40) | 0.77 (0.14, 1.55) | < 0.001 |
TC (mmol/L) | 0.17 (− 0.31, 0.62) | 0.17 (− 0.16, 0.59) | 0.22 (− 0.18, 0.63) | 0.36 (− 0.08, 0.86) | 0.001 |
TG (mmol/L) | − 0.01 (− 0.34, 0.34) | 0.09 (− 0.28, 0.55) | 0.09 (− 0.30, 0.46) | 0.14 (− 0.18, 0.47) | 0.011 |
HDL-C (mmol/L) | 0.11 (− 0.02, 0.25) | 0.06 (− 0.06, 0.18) | 0.05 (− 0.04, 0.15) | 0.04 (− 0.09, 0.17) | < 0.001 |
LDL-C (mmol/L) | − 0.01 (− 0.35, 0.40) | 0.10 (− 0.22, 0.41) | 0.10 (− 0.21, 0.39) | 0.18 (− 0.16, 0.57) | 0.008 |
CRP, mg/L | − 0.01 (− 0.51, 0.43) | 0.02 (− 0.37, 0.54) | 0.03 (− 0.38, 0.56) | 0.12 (− 0.20, 0.71) | 0.003 |