Table 3 Anthropometric measures, metabolic and inflammatory biomarkers before and after the study
Variable | DASH | Control | P |
|---|---|---|---|
(N = 20) | (N = 20) | ||
Weight (Kg) | |||
Baseline | 93.32 ± 19.51 | 93.49 ± 13.98 | 0.976** |
End | 85.57 ± 18.62 | 87.88 ± 13.88 | 0.021*** |
MD (95% CI), P* | −7.75 (−9.34, −6.17), > 0.001 | − 5.61 (− 6.71, − 4.50). < 0.001 | |
BMI (Kg/m2) | |||
Baseline | 33.43 ± 4.09 | 34.02 ± 3.61 | 0.632** |
End | 30.64 ± 4.06 | 31.96 ± 3.57 | 0.025*** |
MD (95% CI), P* | −2.79 (−3.35, −2.22), < 0.001 | −2.06 (−2.47, −1.64), < 0.001 | |
WC (cm) | |||
Baseline | 111.25 ± 12.29 | 109.92 ± 9.80 | 0.708** |
End | 103.32 ± 12.67 | 105.0 ± 9.60 | 0.002*** |
MD (95% CI), P* | −7.92 (−9.58, −6.27), < 0.001 | −4.92 (−5.94, −3.91), < 0.001 | |
HC (cm) | 115.42 ± 10.47 | 115.92 ± 5.84 | |
Baseline | 111.07 ± 11.44 | 112.20 ± 5.99 | 0.853** |
End | −4.35 (−5.22, −3.48), < 0.001 | −3.72 (−4.63, −2.82), < 0.001 | 0.323*** |
MD (95% CI), P* | |||
WHR | 0.95 ± 0.07 | ||
Baseline | 0.96 ± 0.04 | 0.93 ± 0.07 | 0.406** |
End | 0.93 ± 0.05 | −0.01 (−0.02, 0.00), 0.031 | 0.014*** |
MD (95% CI), P* | −0.03 (−0.05, −0.02), < 0.001 | ||
WHtR | |||
Baseline | 0.67 ± 0.06 | 0.66 ± 0.05 | 0.821** |
End | 0.62 ± 0.06 | 0.63 ± 0.05 | 0.002*** |
MD (95% CI), P* | −0.05 (−0.06, −0.04), < 0.001 | −0.03 (−0.04, −0.02), < 0.001 | |
FBS (mg/dl) | |||
Baseline | 93.41 ± 9.63 | 93.12 ± 9.63 | 0.933** |
End | 90.76 ± 5.69 | 90.64 ± 4.69 | 0.923*** |
MD (95% CI), P* | −2.64 (−5.82, 0.53), 0.098 | −0.21 (−0.37, −0.05), 0.013 | |
HbA1c (%) | |||
Baseline | 5.30 ± 0.35 | 5.49 ± 0.49 | < 0.001** |
End | 5.09 ± 0.34 | 5.56 ± 0.32 | < 0.001*** |
MD (95% CI), P* | −2.49 (−7.54, 2.57), 0.314 | 0.07 (−0.08, 0.21), 0.340 | |
TLR-4 (ng/ml) | |||
Baseline | 0.82 ± 0.11 | 0.80 ± 0.17 | 0.656** |
End | 0.70 ± 0.13 | 0.82 ± 0.14 | 0.004*** |
MD (95% CI), P* | −0.13 (−0.20, −0.05),0.003 | 0.02 (−0.05, 0.08), 0.634 | |
MCP-1 (pg/ml) | |||
Baseline | 110.75 ± 7.56 | 11.64 ± 16.48 | 0.828** |
End | 100.44 ± 10.69 | 110.01 ± 11.79 | 0.027*** |
MD (95% CI), P* | −10.32 (−16.36, −4.27), 0.002 | −1.64 (−8.12, 4.85), 0.603 | |
NLR | |||
Baseline | 1.92 ± 0.81 | 1.81 ± 0.64 | 0.238** |
End | 1.94 ± 0.83 | 1.71 ± 0.60 | 0.176*** |
MD (95% CI), P* | 26.51 (19.08, 33.94), < 0.001 | 37.44 (29.64, 45.23), < 0.001 | |
MLR | |||
Baseline | 0.17 ± 0.09 | 0.16 ± 0.07 | 0.732** |
End | 0.23 ± 0.34 | 0.16 ± 0.08 | 0.179*** |
MD (95% CI), P* | 0.06 (−0.09, 0.21), 0.399 | 0.004 (−0.16, 0.02), 0.701 | |
PLR | |||
Baseline | 0.12 ± 0.03 | 0.11 ± 0.4 | 0.731** |
End | 0.12 ± 0.04 | 0.12 ± 0.05 | 0.019*** |
MD (95% CI), P* | −0.002 (−0.010, 0.006), 0.680 | 0.01 (0.001, 0.02), 0.030 | |
SIRI | |||
Baseline | 688.53 ± 437.71 | 720.85 ± 622.22 | 0.850** |
End | 862.13 ± 1139.21 | 706.92 ± 610.50 | 0.151*** |
MD (95% CI), P* | 173.59 (−308.57, 655.76), 0.460 | −13.92 (−68.06, 40.22), 0.597 | |
mHDL | |||
Baseline | 7.59 ± 3.67 | 10.56 ± 8.65 | 0.166** |
End | 13.47 ± 29.77 | 9.44 ± 6.70 | 0.080*** |
MD (95% CI), P* | 5.87 (−7.30, 19.04), 0.362 | − 1.12 (− 2.70, 0.45), 0.152 | |
LPS (pg/ml) | |||
Baseline | 21.66 ± 1.83 | 20.72 ± 2.43 | 0.174** |
End | 18.91 ± 2.98 | 20.90 ± 2.36 | 0.011*** |
MD (95% CI), P* | −2.75 (−4.17, −1.33), < 0.001 | 0.18 (− 1.18, 1.54), 0.785 | |
AST (IU/L) | |||
Baseline | 24.10 ± 10.91 | 26.75 ± 9.28 | 0.413** |
End | 18.40 ± 6.57 | 25.05 ± 8.70 | 0.008*** |
MD (95% CI), P* | −5.70 (−9.42, −1.98), 0.005 | −1.70 (−3.53, 0.13), 0.067 | |
ALT (IU/L) | |||
Baseline | 27.20 ± 14.0 | 37.35 ± 18.37 | 0.057** |
End | 18.75 ± 8.91 | 31.60 ± 16.24 | 0.149*** |
MD (95% CI), P* | −8.45 (−12.89, −4.01), 0.001 | −5.75 (−10.46, −1.04), 0.019 | |