Table 1 Baseline characteristics of subjects
Variables | Placebo (n = 13) | VL_K56 (n = 14) | L_K56 (n = 12) | H_K56 (n = 13) | VH_K56 (n = 14) | p value |
|---|---|---|---|---|---|---|
Gender, F/M | 6/7 | 9/5 | 8/4 | 8/5 | 8/6 | 0.85 |
Height, m | 166.70 ± 10.64 | 165.20 ± 9.28 | 165.30 ± 7.18 | 165.90 ± 10.79 | 163.90 ± 8.65 | 0.95 |
Age, year | 40.15 ± 9.78 | 39.00 ± 7.74 | 38.42 ± 9.59 | 44.92 ± 8.03 | 39.14 ± 10.52 | 0.38 |
Weight, kg | 88.84 ± 23.57 | 80.38 ± 17.26 | 86.96 ± 14.35 | 80.92 ± 17.28 | 81.34 ± 18.60 | 0.67 |
BFM, kg | 34.48 ± 12.18 | 30.96 ± 9.73 | 34.34 ± 7.24 | 30.58 ± 6.74 | 31.13 ± 8.92 | 0.68 |
BMI, kg/m2 | 31.62 ± 5.70 | 29.27 ± 4.77 | 31.72 ± 4.05 | 29.12 ± 3.77 | 29.99 ± 4.71 | 0.45 |
PBF, % | 38.71 ± 7.52 | 38.06 ± 5.62 | 39.42 ± 4.59 | 38.10 ± 5.45 | 38.26 ± 5.54 | 0.97 |
VFA, cm2 | 159.90 ± 49.41 | 146.80 ± 47.05 | 159.20 ± 30.52 | 150.00 ± 34.37 | 146.90 ± 38.15 | 0.86 |
WC, cm | 104.20 ± 15.99 | 99.99 ± 14.46 | 102.40 ± 10.28 | 100.60 ± 12.54 | 99.22 ± 13.17 | 0.88 |
HbA1c, % | 5.70 (0.90) | 5.65 (0.40) | 5.65 (0.60) | 5.60 (0.30) | 5.40 (0.20) | 0.25 |
GA, % | 12.68 ± 2.35 | 11.61 ± 1.43 | 12 ± 1.51 | 12.55 ± 1.27 | 12.11 ± 1.50 | 0.46 |
FBG, mmol/L | 5.60 (0.50) | 5.20 (0.30) | 5.00 (1.05) | 5.00 (1.10) | 4.65 (0.80) | 0.15 |
TCH, mmol/L | 5.06 ± 0.82 | 5.27 ± 0.68 | 5.40 ± 0.66 | 4.94 ± 0.76 | 4.97 ± 0.71 | 0.43 |
TG, mmol/L | 1.87 (1.41) | 1.44 (1.30) | 1.86 (0.86) | 1.36 (0.64) | 1.20 (0.44) | 0.28 |
ALT, U/L | 23.30 (30.80) | 22.95 (23.60) | 28.55 (29.75) | 35.50 (21.70) | 20.60 (18.40) | 0.35 |
AST, U/L | 16.10 (16.60) | 18.35 (6.70) | 18.85 (12.85) | 24.30 (9.10) | 16.55 (5.40) | 0.30 |
Creatinine, μmol/L | 79.15 ± 14.65 | 75.11 ± 11.09 | 73.97 ± 10.94 | 71.20 ± 11.92 | 75.11 ± 14.71 | 0.63 |
Urea, mmol/L | 5.20 (0.80) | 5.10 (0.90) | 5.20 (2.20) | 4.80 (1.90) | 5.35 (2.10) | 0.90 |