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Table 2 Predictive performance of models for incident DR with or without ChE

From: Serum cholinesterase is associated with incident diabetic retinopathy: the Shanghai Nicheng cohort study

 

AUC

  

IDI

   

NRI

 
 

AUC (95% CI)

P value

 

IDI

rIDI

P value

 

NRI

P value

Model 1†

0.65 (0.59–0.71)

  

Ref.

Ref.

  

Ref.

 

+ ChE

0.67 (0.60–0.73)

0.320

 

0.01

0.36

0.024

 

0.31

0.010

Model 2‡

0.65 (0.60–0.71)

  

Ref. 

Ref.

  

Ref.

 

+ ChE

0.66 (0.60–0.72)

0.686

 

0.01

0.54

0.019

 

0.27

0.025

  1. ChE was each 1-SD loge-transformed. Model 1 and model 2 were predictive models established in previous studies
  2. † Independent variables included sex, diabetes duration, HbA1c, SBP, albuminuria, creatinine clearance, and glucose-lowering treatment
  3. ‡ Independent variables included age, diabetes duration, 2 h-PG, HbA1c, UCR, albuminuria, and SBP
  4. Abbreviations: Ref, reference; ChE, cholinesterase; DR, diabetic retinopathy; IDI, integrated discrimination improvement; rIDI, relative integrated discrimination improvement; NRI, net reclassification improvement; HbA1c, hemoglobin A1c; SBP, systolic blood pressure; 2 h-PG, 2 h- postprandial blood glucose; UCR, urinary creatinine
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Nutrition & Metabolism

ISSN: 1743-7075

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