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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE−/− mice

Fig. 1

Lycopene supplementation inhibited the atherosclerosis of aortic sinus in HFD-fed ApoE−/− mice. ApoE−/− mice were fed a low-fat diet, a high-fat diet supplemented with or without 0.1% lycopene (w/w) for 19 weeks. (A) Oil red O staining of the aortic sinus is presented graphically (40×magnification), as described in Materials and Methods. The larger the area of red plaque, the deeper the atherosclerosis. (B) The ratio of the area of atherosclerotic plaque to the area of the aortic sinus was analyzed by Image J software. Data are presented as the mean ± SD (n = 8 per group); ap < 0.05 compared with the control group; bp < 0.05 compared with the high-fat diet group. HFD, high-fat diet; LY, lycopene

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Nutrition & Metabolism

ISSN: 1743-7075

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